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Copyright © 2010 Ryan P. Murphy. RED SLIDE: These are notes that are very important and should be recorded in your science journal. Copyright.

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Presentation on theme: "Copyright © 2010 Ryan P. Murphy. RED SLIDE: These are notes that are very important and should be recorded in your science journal. Copyright."— Presentation transcript:

1 Copyright © 2010 Ryan P. Murphy

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8 RED SLIDE: These are notes that are very important and should be recorded in your science journal. Copyright © 2010 Ryan P. Murphy

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10 Please use this red line

11 -Please make notes legible and use indentations when appropriate. Please use this red line

12 - Please make notes legible and use indentations when appropriate. Please use this red line

13 -Please make notes legible and use indentations when appropriate. -Example of indent.

14 -Please make notes legible and use indentations when appropriate. -Example of indent. -Skip a line between topics

15 -Please make notes legible and use indentations when appropriate. -Example of indent. -Skip a line between topics -Don’t skip pages

16 -Please make notes legible and use indentations when appropriate. -Example of indent. -Skip a line between topics -Don’t skip pages -Make visuals clear and well drawn.

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18 -Please make notes legible and use indentations when appropriate. -Example of indent. -Skip a line between topics -Don’t skip pages -Make visuals clear and well drawn. Please Label Phosphate Backbone Double Helix Nitrogen Base

19 RED SLIDE: These are notes that are very important and should be recorded in your science journal. BLACK SLIDE: Pay attention, follow directions, complete projects as described and answer required questions neatly. Copyright © 2010 Ryan P. Murphy

20 Keep an eye out for “The-Owl” and raise your hand as soon as you see him. –He will be hiding somewhere in the slideshow Copyright © 2010 Ryan P. Murphy

21 Keep an eye out for “The-Owl” and raise your hand as soon as you see him. –He will be hiding somewhere in the slideshow “Hoot, Hoot” “Good Luck!” Copyright © 2010 Ryan P. Murphy

22 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

23 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

24 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

25 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

26 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

27 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

28 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

29 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

30 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

31 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

32 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

33 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

34 Overview of topics in this unit –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

35 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

36 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

37 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

38 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

39 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

40 Overview of topics in Part I –DNA Extraction from split pea –Discovery of DNA –DNA’s Structure –Nucleotides –Building a DNA model –DNA replication –Cell Division –Chromosomes –Phases of Mitosis

41 Copyright © 2010 Ryan P. Murphy

42 How old are you? ? Copyright © 2010 Ryan P. Murphy

43 Answer: Billions of years old. Copyright © 2010 Ryan P. Murphy This Product Belongs to Ryan P. Murphy Copyright 2010

44 Answer: Billions of years old. –How? Copyright © 2010 Ryan P. Murphy This Product Belongs to Ryan P. Murphy Copyright 2010

45 The back story of our lives are that we are the product of billions of years of evolution. The very DNA that allows us to pass on our genetic information to our offspring has its roots in primitive microbes that existed billions of years ago. Copyright © 2010 Ryan P. Murphy

46 The back story of our lives are that we are the product of billions of years of evolution. The very DNA that allows us to pass on our genetic information to our offspring has its roots in primitive microbes that existed billions of years ago. Copyright © 2010 Ryan P. Murphy

47 DNA Extraction Available Sheet

48 Activity! Extracting the Code of Life. –Lab handout can be found in the activities folder. –http://learn.genetics.utah.edu/content/labs/ext raction/howto/ (More Information)http://learn.genetics.utah.edu/content/labs/ext raction/howto/ The Instructions For Life

49 Activity! DNA Extraction Procedure: Part I 1.) One class member measures out 100ml of split peas and add to blender. 2.) Add 1ml of table salt to blender. 3.) Add 200 ml of cold water. 4.) Cover and blend on high for 15-20 seconds. 5.) Pour contents through strainer into another container (plastic cup). Copyright © 2010 Ryan P. Murphy

50 Activity! DNA Extraction Procedure: Part II 6.) Add 30 ml of liquid detergent and mix in the container. 7.) Let the mixture sit for 5-10 minutes (clean up area during this time) 8.) Pour the mixture into test tubes equally. 9.) Add a pinch of enzymes to each container. “Gently” very gently swirl for 1 minute. Copyright © 2010 Ryan P. Murphy

51 Activity! DNA Extraction Procedure: Part III 7.) Tilt your test tube and slowly pour rubbing alcohol (70-95% isopropyl or ethyl alcohol) into the tube down the side so that it forms a layer on top of the pea mixture. Pour until you have about the same amount of alcohol in the tube as pea mixture. 8.) DNA will rise into the alcohol layer from the pea layer. You can use a wooden stick (cotton swab) or other hook to draw the DNA into the alcohol. Copyright © 2010 Ryan P. Murphy

52 Procedure: 1) One class member measures out 100ml of split peas and add to blender. 2) Add 1ml of table salt to blender. 3) Add 200 ml of cold water. 4) Cover and blend on high for 15-20 seconds. 5) Pour contents through strainer into another container (plastic cup). 6) Add 30 ml of liquid detergent and mix in the container. 7) Let the mixture sit for 5-10 minutes (clean up area during this time). 8) Pour the mixture into test tubes equally. 9) Add a pinch of enzymes to each container. 10) “Gently” very gently swirl for 1 minute. 11) Tilt your test tube and slowly pour rubbing alcohol (70-95% isopropyl or ethyl alcohol) into the tube down the side so that it forms a layer on top of the pea mixture. Pour until you have about the same amount of alcohol in the tube as pea mixture. 12) DNA will rise into the alcohol layer from the pea layer. You can use a wooden stick (cotton swab) or other hook to draw the DNA into the alcohol. http://www.biologyjunction.com/extracting_dna.htm

53 Activity! DNA Extraction –Directions will be provided. Copyright © 2010 Ryan P. Murphy

54 Activity! DNA Extraction –Directions will be provided. Copyright © 2010 Ryan P. Murphy

55 Activity! DNA Extraction –Directions will be provided. Copyright © 2010 Ryan P. Murphy

56 Activity! DNA Extraction –Directions will be provided. Copyright © 2010 Ryan P. Murphy

57 Activity! DNA Extraction –Directions will be provided. Copyright © 2010 Ryan P. Murphy

58 Activity! DNA Extraction –Directions will be provided. Copyright © 2010 Ryan P. Murphy

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60 The meat tenderizer was added to break down the protein that the DNA is wrapped around. This allows the protein to be extracted. Copyright © 2010 Ryan P. Murphy

61 Did your final extraction look like this? –This is DNA, the genetic molecules in each cell. Copyright © 2010 Ryan P. Murphy Learn more about DNA extraction at… http://www.chem.umn.edu/services/lecturedemo/info/DNA.htm http://www.chem.umn.edu/services/lecturedemo/info/DNA.htm

62 DNA DNA - - - - Copyright © 2010 Ryan P. Murphy

63 DNA: Deoxyribose Nucleic Acid. DNA: Deoxyribose Nucleic Acid. Copyright © 2010 Ryan P. Murphy

64 Shape is called double helix. Shape is called double helix. Copyright © 2010 Ryan P. Murphy

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66 DNA is a polymer (Long molecule). DNA is a polymer (Long molecule). Copyright © 2010 Ryan P. Murphy

67 DNA is a polymer (Long molecule). DNA is a polymer (Long molecule). Copyright © 2010 Ryan P. Murphy A tightly wound package of DNA.

68 Activity! How long is the DNA chain inside of a cell? –Take your best guess. Copyright © 2010 Ryan P. Murphy

69 Answer: The DNA in cells can hold lots of information and are very long. –Each cell has about 1.8 meters (6 feet) of DNA. 1.8 meters of DNA Copyright © 2010 Ryan P. Murphy

70 Video! DNA wrapping. Shows how 1.8 meters of DNA can be found in a single cell. –http://www.youtube.com/watch?v=AF2wwMReTf8http://www.youtube.com/watch?v=AF2wwMReTf8 Copyright © 2010 Ryan P. Murphy

71 The units of DNA are called nucleotides. The units of DNA are called nucleotides. Copyright © 2010 Ryan P. Murphy

72 DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

73 DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

74 DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

75 DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

76 DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

77 DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

78 DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

79 DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

80 DNA has the information for our cells to make proteins. DNA has the information for our cells to make proteins. Copyright © 2010 Ryan P. Murphy

81 DNA through transcription makes mRNA. DNA through transcription makes mRNA. mRNA = Messenger RNA. mRNA = Messenger RNA. Copyright © 2010 Ryan P. Murphy

82 Transcription, Learn more at http://biology.about.com/od/cellularpro cesses/ss/Dna-Transcription.htm http://biology.about.com/od/cellularpro cesses/ss/Dna-Transcription.htm

83 mRNA through translation makes proteins with the help of ribosomes. mRNA through translation makes proteins with the help of ribosomes. Copyright © 2010 Ryan P. Murphy

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123 Video Link! Transcription and Translation. –http://www.youtube.com/watch?v=41_Ne5mhttp://www.youtube.com/watch?v=41_Ne5m

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125 Important Note: Most DNA is found in the nucleus.

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127 Important Note: Most DNA is found in the nucleus. Small amounts of DNA are found in the mitochondria organelle (mtDNA) –Learn more abaout mtDNA at http://en.wikipedia.org/wiki/Mitochondrial_DNAhttp://en.wikipedia.org/wiki/Mitochondrial_DNA

128 Important Note: Most DNA is found in the nucleus. Small amounts of DNA are found in the mitochondria organelle (mtDNA) –Learn more http://en.wikipedia.org/wiki/Mitochondrial_DNAhttp://en.wikipedia.org/wiki/Mitochondrial_DNA

129 You can now do this question for homework.

130 Watson and Crick (1953) Discovered structure of DNA. –One of the most important biological discoveries in the last 100 years. Copyright © 2010 Ryan P. Murphy

131 Watson and Crick (1953) Discovered structure of DNA. –One of the most important biological discoveries in the last 100 years. Copyright © 2010 Ryan P. Murphy

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133 Watson and Crick were able to figure out that one strand went up and one went down.

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136 Watson and Crick also found that if they paired Thymine with Adenine and Guanine with Cytosine DNA would look uniform.

137 Watson and Crick were able to figure out that one strand went up and one went down. Watson and Crick also found that if they paired Thymine with Adenine and Guanine with Cytosine DNA would look uniform. Learn more at… http://www.nobelprize.org/educa tional/medicine/dna_double_heli x/readmore.html?referer=www.cl ickfind.com.au

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139 James Watson

140 Francis Crick

141 “Am I Watson or Crick?”

142 “I am James Watson.”

143 “Am I Watson or Crick?”

144 “I am Francis Crick.”

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146 Francis Crick

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148 James Watson

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152 Francis Crick

153 “What year did we discover the structure of DNA.”

154 1953

155 Activity Reading. Who discovered DNA? –Please complete 3 of the 5 questions on the last page.

156 Please answer 3 of the 5 questions below from the difficult reading. –1.) Name four people in this article and how they contributed to the discovery of DNA’s structure? –2.) What role did Maurice Wilkins play in the discovery of DNA’s structure? –3.) What two things in DNA’s structure did Watson and Crick figure out that Rosalind Franklin missed? –4.) Describe the relationship between of Rosalind Franklin to Watson, Crick, and Wilkins? –5.) How does getting things done first / taking risks relate to this article? –6.) Find three words that you did not know from the reading and use a dictionary / resource to define them? –7.) Create a comic book sequence between Rosalind Franklin, Maurice Wilkins, James Watson, and Francis Crick from something discussed in the article.

157 Rosalind Franklin? Who is she? Copyright © 2010 Ryan P. Murphy

158 She took X-Ray pictures of DNA’s structure and lectured about phosphate being a part of the outside of the molecule. Copyright © 2010 Ryan P. Murphy

159 She took X-Ray pictures of DNA’s structure and lectured about phosphate being a part of the outside of the molecule. – Watson attended her lecture. Copyright © 2010 Ryan P. Murphy

160 Watson and Crick used her photograph and lectures to create a failed model of the helix. Copyright © 2010 Ryan P. Murphy

161 Watson and Crick used her photograph and lectures to create a failed model of the helix. –Maurice Wilkins who was working with Rosalind Franklin showed Watson her experiments. Copyright © 2010 Ryan P. Murphy

162 In 1962, Copyright © 2010 Ryan P. Murphy

163 In 1962, Watson, Copyright © 2010 Ryan P. Murphy

164 In 1962, Watson, Crick, Copyright © 2010 Ryan P. Murphy

165 In 1962, Watson, Crick, and Wilkins Copyright © 2010 Ryan P. Murphy

166 In 1962, Watson, Crick, and Wilkins won the Nobel Prize for physiology/medicine. Copyright © 2010 Ryan P. Murphy

167 In 1962, Watson, Crick, and Wilkins won the Nobel Prize for physiology/medicine. Copyright © 2010 Ryan P. Murphy

168 In 1962, Watson, Crick, and Wilkins won the Nobel Prize for physiology/medicine. –Franklin had died of Ovarian Cancer. Copyright © 2010 Ryan P. Murphy

169 In 1962, Watson, Crick, and Wilkins won the Nobel Prize for physiology/medicine, –Franklin had died of Ovarian Cancer. –The cancer that killed her may have been caused by working with X-Rays.

170 In 1962, Watson, Crick, and Wilkins won the Nobel Prize for physiology/medicine, –Franklin had died of Ovarian Cancer. –The cancer that killed her may have been caused by working with X-Rays. –The Nobel Prize only goes to living recipients, and can only be shared among three winners.

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172 Copyright © 2010 Ryan P. Murphy

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178 Who thinks we should give an honorary Nobel Prize to Rosalind Franklin? Copyright © 2010 Ryan P. Murphy

179 Who thinks we should give an honorary Nobel Prize to Rosalind Franklin? –Lets give a short round of applause to Rosalind Franklin. –“Our Lady of DNA” Copyright © 2010 Ryan P. Murphy

180 Who thinks we should give an honorary Nobel Prize to Rosalind Franklin? –Lets give a short round of applause to Rosalind Franklin. –“Our Lady of DNA” Copyright © 2010 Ryan P. Murphy Learn more about Rosalind Franklin at… http://www.biography.com/people/rosalind- franklin-9301344 http://www.biography.com/people/rosalind- franklin-9301344

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189 You can now do this question for homework.

190 Activity! Draw DNA in Detail. Copyright © 2010 Ryan P. Murphy

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195 A AA G T C T T

196 Each unit called a nucleotide of DNA consists of 3 parts. Each unit called a nucleotide of DNA consists of 3 parts. - - - Copyright © 2010 Ryan P. Murphy

197 A AA G T C T T Nucleotide

198 Phosphate backbone Phosphate backbone Copyright © 2010 Ryan P. Murphy

199 A AA G T C T T Phosphate Backbone Copyright © 2010 Ryan P. Murphy

200 A 5-carbon sugar (deoxyribose) A 5-carbon sugar (deoxyribose) Copyright © 2010 Ryan P. Murphy

201 A AA G T C T T Ribose Sugar Copyright © 2010 Ryan P. Murphy

202 A nitrogen base attached to the sugar A nitrogen base attached to the sugar Copyright © 2010 Ryan P. Murphy

203 A AA G T C T T Nitrogen Base Copyright © 2010 Ryan P. Murphy

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209 Nucleic Acids – P O N C H (Nucleotide)Nucleic Acids – P O N C H (Nucleotide) Copyright © 2010 Ryan P. Murphy

210 Nucleic Acids – P O N C H (Nucleotide)Nucleic Acids – P O N C H (Nucleotide) Copyright © 2010 Ryan P. Murphy

211 Nucleic Acids – P O N C H (Nucleotide)Nucleic Acids – P O N C H (Nucleotide) Copyright © 2010 Ryan P. Murphy

212 Nucleic Acids – P O N C H (Nucleotide)Nucleic Acids – P O N C H (Nucleotide) Copyright © 2010 Ryan P. Murphy

213 Nucleic Acids – P O N C H (Nucleotide)Nucleic Acids – P O N C H (Nucleotide) Copyright © 2010 Ryan P. Murphy

214 Nucleic Acids – P O N C H (Nucleotide)Nucleic Acids – P O N C H (Nucleotide) Copyright © 2010 Ryan P. Murphy

215 Nucleic Acids – P O N C H (Nucleotide)Nucleic Acids – P O N C H (Nucleotide) Copyright © 2010 Ryan P. Murphy

216 Nucleic Acids – P O N C H (Nucleotide)Nucleic Acids – P O N C H (Nucleotide) Copyright © 2010 Ryan P. Murphy

217 Nucleic Acids – P O N C H (Nucleotide)Nucleic Acids – P O N C H (Nucleotide) Copyright © 2010 Ryan P. Murphy

218 Nucleic Acids – P O N C H (Nucleotide)Nucleic Acids – P O N C H (Nucleotide) Copyright © 2010 Ryan P. Murphy

219 Nucleic Acids – P O N C H (Nucleotide)Nucleic Acids – P O N C H (Nucleotide) Copyright © 2010 Ryan P. Murphy

220 There are four different types of nucleotides found in DNA There are four different types of nucleotides found in DNA A is for adenine A is for adenine G is for guanine G is for guanine C is for cytosine C is for cytosine T is for thymine T is for thymine Copyright © 2010 Ryan P. Murphy

221 There are four different types of nucleotides found in DNA There are four different types of nucleotides found in DNA A is for adenine A is for adenine G is for guanine G is for guanine C is for cytosine C is for cytosine T is for thymine T is for thymine Copyright © 2010 Ryan P. Murphy

222 There are four different types of nucleotides found in DNA There are four different types of nucleotides found in DNA A is for adenine A is for adenine G is for guanine G is for guanine C is for cytosine C is for cytosine T is for thymine T is for thymine Copyright © 2010 Ryan P. Murphy

223 There are four different types of nucleotides found in DNA There are four different types of nucleotides found in DNA A is for adenine A is for adenine G is for guanine G is for guanine C is for cytosine C is for cytosine T is for thymine T is for thymine Copyright © 2010 Ryan P. Murphy

224 There are four different types of nucleotides found in DNA There are four different types of nucleotides found in DNA A is for adenine A is for adenine G is for guanine G is for guanine C is for cytosine C is for cytosine T is for thymine T is for thymine Copyright © 2010 Ryan P. Murphy

225 There are four different types of nucleotides found in DNA There are four different types of nucleotides found in DNA A is for adenine A is for adenine G is for guanine G is for guanine C is for cytosine C is for cytosine T is for thymine T is for thymine Copyright © 2010 Ryan P. Murphy –Learn more about the structure of DNA at http://ghr.nlm.nih.gov/ha ndbook/basics/dna http://ghr.nlm.nih.gov/ha ndbook/basics/dna

226 Copyright © 2010 Ryan P. Murphy

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230 A AA G T C T T

231 A AA G T C T T Nucleotide

232 A AA G T C T T Phosphate Backbone Copyright © 2010 Ryan P. Murphy

233 A AA G T C T T Ribose Sugar Copyright © 2010 Ryan P. Murphy

234 A AA G T C T T Nitrogen Base Copyright © 2010 Ryan P. Murphy

235 Can you touch the following on this moving image of the double helix. Copyright © 2010 Ryan P. Murphy

236 Can you touch the following on this moving image of the double helix. Phosphate Backbone Phosphate Backbone Copyright © 2010 Ryan P. Murphy

237 Can you touch the following on this moving image of the double helix. Phosphate Backbone Phosphate Backbone Ribose sugar Copyright © 2010 Ryan P. Murphy

238 Can you touch the following on this moving image of the double helix. Phosphate Backbone Phosphate Backbone Ribose sugar Nitrogen Base Copyright © 2010 Ryan P. Murphy

239 A goes with T A goes with T C goes with G C goes with G WRONG! T – C or G - A WRONG! T – C or G - A Copyright © 2010 Ryan P. Murphy

240 A goes with T A goes with T C goes with G C goes with G WRONG! T – C or G - A WRONG! T – C or G - A Copyright © 2010 Ryan P. Murphy

241 A goes with T A goes with T C goes with G C goes with G WRONG! T – C or G - A WRONG! T – C or G - A Copyright © 2010 Ryan P. Murphy

242 A goes with T A goes with T C goes with G C goes with G WRONG! T – C or G - A WRONG! T – C or G - A Copyright © 2010 Ryan P. Murphy

243 Activity! Which of the base pairs below is incorrect. Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Adenine Adenine – Thymine Guanine – Cytosine Copyright © 2010 Ryan P. Murphy

244 Answers! Which of the base pairs below is incorrect. Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Adenine Adenine – Thymine Guanine – Cytosine Same challenge next slide  Copyright © 2010 Ryan P. Murphy

245 Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Guanine – Cytosine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Guanine – Cytosine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Guanine – Cytosine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Guanine – Cytosine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Guanine – Cytosine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Guanine – Cytosine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Adenine – Adenine Guanine – Cytosine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Guanine – Cytosine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Copyright © 2010 Ryan P. Murphy

246 Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Guanine – Cytosine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Guanine – Cytosine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Guanine – Cytosine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Guanine – Cytosine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Guanine – Cytosine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Guanine – Cytosine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Adenine – Adenine Guanine – Cytosine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Cytosine - Guanine Adenine –- Thymine Guanine –- Cytosine Thymine - Adenine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Guanine – Cytosine Adenine -- Thymine Cytosine – Guanine Adenine – Thymine Copyright © 2010 Ryan P. Murphy

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248 This PowerPoint is one small part of my DNA and Genetics Unit. This unit includes… –A five part 3,000 slide PowerPoint roadmap. –14 page bundled homework package, answer keys, lesson notes, rubrics, materials list, guide, and much more. –PowerPoint Review Game, games, flashcards, crosswords, and more. –http://sciencepowerpoint.com/DNA_Genetics _Unit.htmlhttp://sciencepowerpoint.com/DNA_Genetics _Unit.html

249 DNA Review Game

250 “AYE” Advance Your Exploration ELA and Literacy Opportunity Worksheet –Visit some of the many provided links or.. –Articles can be found at (w/ membership to NABT and NSTA) http://www.nabt.org/websites/institution/index.php?p= 1http://www.nabt.org/websites/institution/index.php?p= 1 http://learningcenter.nsta.org/browse_journals.aspx?j ournal=tsthttp://learningcenter.nsta.org/browse_journals.aspx?j ournal=tst Please visit at least one of the “learn more” educational links provided in this unit and complete this worksheet.

251 “AYE” Advance Your Exploration ELA and Literacy Opportunity Worksheet –Visit some of the many provided links or.. –Articles can be found at (w/ membership to NABT and NSTA) http://www.nabt.org/websites/institution/index.php?p=1 http://learningcenter.nsta.org/browse_journals.aspx?jo urnal=tsthttp://learningcenter.nsta.org/browse_journals.aspx?jo urnal=tst

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253 Areas of Focus within The DNA and Genetics Unit: DNA, DNA Extraction, Structure of DNA, Discovery of the Double Helix, Rosalind Franklin, Nucleotides, RNA, Cell Division, Mitosis, Phases of Mitosis, Chromosomes, Cancer, Ways to Avoid Cancer, What is Inside a Cigarette?, Facts about Smoking?, Anti-Smoking Ads, Meiosis, Phases in Meiosis, Mendelian Genetics, Gregor Mendel, Punnett Squares, Probability, Dihybrid Cross, Codominance, Bio-Ethics, Stem Cell Debate, Cloning Debate –Full Unit found at… –http://sciencepowerpoint.com/DNA_Genetics_Unit.htmlhttp://sciencepowerpoint.com/DNA_Genetics_Unit.html

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258 Please visit the links below to learn more about each of the units in this curriculum –These units take me about four years to complete with my students in grades 5-10. Earth Science UnitsExtended Tour Link and Curriculum Guide Geology Topics Unit http://sciencepowerpoint.com/Geology_Unit.html Astronomy Topics Unit http://sciencepowerpoint.com/Astronomy_Unit.html Weather and Climate Unit http://sciencepowerpoint.com/Weather_Climate_Unit.html Soil Science, Weathering, More http://sciencepowerpoint.com/Soil_and_Glaciers_Unit.html Water Unit http://sciencepowerpoint.com/Water_Molecule_Unit.html Rivers Unit http://sciencepowerpoint.com/River_and_Water_Quality_Unit.html = Easier = More Difficult = Most Difficult – 5 th – 7 th grade 6 th – 8 th grade 8 th – 10 th grade

259 Physical Science UnitsExtended Tour Link and Curriculum Guide Science Skills Unit http://sciencepowerpoint.com/Science_Introduction_Lab_Safety_Metric_Methods. html Motion and Machines Unit http://sciencepowerpoint.com/Newtons_Laws_Motion_Machines_Unit.html Matter, Energy, Envs. Unit http://sciencepowerpoint.com/Energy_Topics_Unit.html Atoms and Periodic Table Unit http://sciencepowerpoint.com/Atoms_Periodic_Table_of_Elements_Unit.html Life Science UnitsExtended Tour Link and Curriculum Guide Human Body / Health Topics http://sciencepowerpoint.com/Human_Body_Systems_and_Health_Topics_Unit.html DNA and Genetics Unit http://sciencepowerpoint.com/DNA_Genetics_Unit.html Cell Biology Unit http://sciencepowerpoint.com/Cellular_Biology_Unit.html Infectious Diseases Unit http://sciencepowerpoint.com/Infectious_Diseases_Unit.html Taxonomy and Classification Unit http://sciencepowerpoint.com/Taxonomy_Classification_Unit.html Evolution / Natural Selection Unit http://sciencepowerpoint.com/Evolution_Natural_Selection_Unit.html Botany Topics Unit http://sciencepowerpoint.com/Plant_Botany_Unit.html Ecology Feeding Levels Unit http://sciencepowerpoint.com/Ecology_Feeding_Levels_Unit.htm Ecology Interactions Unit http://sciencepowerpoint.com/Ecology_Interactions_Unit.html Ecology Abiotic Factors Unit http://sciencepowerpoint.com/Ecology_Abiotic_Factors_Unit.html

260 Thank you for your time and interest in this curriculum tour. Please visit the welcome / guide on how a unit works and link to the many unit previews to see the PowerPoint slideshows, bundled homework, review games, unit notes, and much more. Thank you for your interest and please feel free to contact me with any questions you may have. Best wishes. Sincerely, Ryan Murphy M.Ed ryemurf@gmail.com

261 The entire four year curriculum can be found at... http://sciencepowerpoint.com/ Please feel free to contact me with any questions you may have. Thank you for your interest in this curriculum. http://sciencepowerpoint.com/ Sincerely, Ryan Murphy M.Ed www.sciencepowerpoint@gmail.com


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