2. CAPILLARY ELECTROPHORESIS SYSTEMS CAPEL

3. CAPILLARY ELECTROPHORESIS SYSTEMS CAPEL CERTIFICATION Simultaneous quantitative determination of several components in a complex mixture

4. ADVANTAGES CAPEL-SERIES  High separation efficiency  Low reagent consumption  Simple sample preparation  Compact benchtop design  Autosamplers (10 inlet and and 10 outlet vials) in CAPEL-104, CAPEL-104T, and CAPEL-105  Implementation of various methods (Capillary Zone Electrophoresis, Micellar electrokinetic chromatography, Capillaryisoelectric focusing, capillary gel electrophoresis, capillary isotachophoresis)

5. ELECTROOSMOTIC FLOW (EOF) R – Si-OH  R – Si-O - + H + K+K+ A-A- EOF + _ pH > 3.0 Both anions and cations can be analysed in one run                

6. BASIC FEATURES CAPEL-103Р, 103РТ CAPEL-104, 104Т CAPEL-105 wavelength 254 nm autosampler liquid cooling (model 104Т) wavelength 254 nm manual operation mode liquid cooling (model 103РТ) wavelength 190-380 nm autosampler liquid cooling

7. MAJOR APPLICATIONS  pesticides  inorganic ions  phenols Environment Pharmacology  medicines formulations  pharmacokinetics Food  preservatives  dyes  target compounds, etc. Clinical diagnostics  proteomics  DNA / RNA  affinity studies  immunoanalyses Forensic Investigations  drugs  explosives  lethal markers, etc. Chemical industry

8. ANALYSIS OF PSYCHOTROPIC DRUGS MECK separation of carbamazepine and its main metabolites Chiral separation of carbamazepine metabolite

9. ANALYSIS OF ANTIEPILEPTIC DRUGS Microemulsion EKC of 6 closely related antiepileptic drugs Selectivity changes are seen with different organic modifiers

10. 2 4 6 8 min mAU ANALYSIS OF WATER – SOLUBLE VITAMINS Buffer0.01M borate, pH 9.8 Samplestandard solution of vitamins Capillaryl/L 50/60 cm, id 75 µm Injection600 mbar * s Voltage+20 kV Detection 254 nm 1 – vitamin В 1 2 – vitamin В 12 3 – vitamin В 2 4 – vitamin В 6 5 – ascorbic acid 6 – nicotinic acid 7 – folic acid

11. ANALYSIS OF MEDICALLY RELEVANT PEPTIDES ANALYSIS OF MEDICALLY RELEVANT PEPTIDES 1-antithrombine 2-bradikinine 3-angiotensin I 4-angiotensine II Buffer 10 mM phosphate, pH 2.5 Capillary 26 / 35 cm, 50µm ID Injection 150 mbar x sec Voltage25 kV Sample 10 µg/mL each

12. ANALYSIS OF THE CATION COMPOSITION OF THE PORTABLE, NATURAL AND WASTE WATER Buffer6 mmol benzimidazole, 2.5 mmol tartaric acid, 2.0 mmol 18-crown-6 Samplecalibration solution Capillaryl/L 50/60 cm, id 75 µm Injection150 mbar * s Voltage+10 kV Detection254 nm, indirect 1 – cesium 2 – ammonium 3 – potassium 4 – sodium 5 – magnesium 6 – lithium 7 – strontium 8 – barium 9 – calcium            

13. ANALYSIS OF THE ANION COMPOSITION OF THE PORTABLE, NATURAL AND WASTE WATER Buffer5 mmol chromate, 20 mmol DEA, 1.65 mmol CTAB Samplecalibration solution, 5 mg/l of each anion (fluoride  2.5 mg/l) Capillaryl/L 50/ 60 cm, id 75 µm Injection300 mbar * s Voltage  17 kV Detection254 nm, indirect 1  chloride 2  nitrite 3  sulfate 4  nitrate 5  fluoride 6  phosphate *  bromide hollow **  hydrocarbonate           

14. ANALYSIS OF PESTICIDES OF SYMMETRIC TRIAZINE GROUP Buffer10 mmol sodium borate, 32 mmol SDS Sampletest solution, 2.5 mg/l of each compound Capillaryl/L 60/70 cm, id 75 µm Injection900 mbar * s Voltage+20 kV Detection229 nm 1 – simazine 2 – atrazine 3 – propazine 4 – prometryne       

15.                ANALYSIS OF SYNTHETIC DYES Buffer5 mmol phosphate, 5 mmol hydrocarbonate, pH 10.5 Samplestandard mixture of dyes Capillaryl/L 50/60 cm, id 75 µm Injection600 mbar*s Voltage+20 kV Detection254 nm 1 – Rhodamine B (C.I. 45170) 2 – Patent Blue V (E131, C.I. 42051) 3 – Orange I (C.I. 14600) 4 – Acid Green S (E142, C.I. 44090) 5 – Acid Violet 5BN (C.I. 42650) 6 – Quinoline Yellow (E104, C.I. 47005) 7 – Sunset Yellow FCF (E110, C.I. 15985) 8 – Tartrazine (E102, C.I. 19140) 9 – Azorubine (E122, C.I. 14720) 10 – Amaranth (E123, C.I. 16185) 11 – Chrysoine (C.I. 14270) 12 – Brilliant black PN (E151, C.I. 28440) 13 – Indigotin (E132, C.I. 73015) 14 – Brilliant Blue FCF (E133, C.I. 42090)

16. ANALYSIS OF BENZOIC ACID DERIVATIVES Buffer 25 mM borate pH 9.18 Capillary 26 / 35 cm, 50µm ID Injection 150 mbar x sec Voltage 25 kV

17. APPLICATIONS  Determination of inorganic anions in water samples Determination of inorganic anions in water samples  Determination of inorganic cations in water samples Determination of inorganic cations in water samples  Determination of phenoxycarboxylic acid herbicides in water Determination of phenoxycarboxylic acid herbicides in water  Determination of caffeine and preservatives in beverages Determination of caffeine and preservatives in beverages

18. SPECIFICATION Capel-103Capel-104Capel-105 Detector Line-source lamp, 254 nm Light source - deuterium lamp 190 – 380 nm Operating mode Manual Fully automated, programmable Capillary cooling Air-forced with ambient t°C In ver.(T) – thermostatic liquid cooling with pre-set t°C Liquid cooling with thermostabilisation, from -10 up to +30°C with respect to ambient Sampler Manually operated for 4 vials Autosampler, 10 inlet, 10 outlet vials

19. CONTACTS LUMEX LTD. 19, Moskovskiy pr., St. Petersburg, 190005 Russia Phone: +7 (812) 718-5390, +7 (812) 718-5391 Fax: +7 (812) 316-6538 E-mail: sales@lumex.ru, is@lumex.ru; http://www.lumex.rusales@lumex.ruis@lumex.ruwww.lumex.ru LUMEX INTERNATIONAL 4736 Lee Hwy, suite 203, Arlington VA 22207, USA Phone/Fax: +1 (703) 243-7103; E-mail: info@lumexint.com; http://www.lumexint.cominfo@lumexint.comwww.lumexint.com OhioLumex Co. 9263, Ravenna Rd., Unit A3 Twinsburg, OH 44087 USA Phone: +1 (888) 876-2611; +1 (330) 405-0837 Fax: +1 (330) 405-0847 E-mail: Siperst@yahoo.com, mail@ohiolumex.com; http://www.ohiolumex.comSiperst@yahoo.commail@ohiolumex.comwww.ohiolumex.com