1. THE PHASES OF MITOSIS Claire Stevens

2. Interphase– Growth and preparation DNA is in its chromatin state Cell grows bigger The cell is making protein necessary for its survival

3. Interphase--Replication It may not look like anything has changed in the cell but…. An enzyme separates the DNA into two stands here DNA unwinds The original DNA strand is a sort of template for a new side to form around Most organelles will be replicated during this stage

4. Interphase-Continuing growth and preparation The cell is continuing to grow and make proteins The chromatin has not coiled up into chromosomes as of yet

5. Early prophase Spindle fibers start to form from the centrioles The nucleolus has disappeared from the nucleus The nuclear membrane begins to break down DNA coils up into chromosomes

6. Early prophase-continue The centrioles with the spindle fibers move towards the poles of the cell The nuclear membrane continues to break down

7. Early prophase- continue The centrioles and spindle fibers are now almost at the poles of the cell The cell membrane has almost completely disintegrated

8. Late prophase The spindle fibers are now fully formed. The spindle fibers attach to the chromosomes at the centromere The nuclear membrane has completely disappeared The centrioles are completely at the poles

9. Late prophase- continue The spindle fibers are starting to pull the chromosomes into a line across the equator of the cell

10. Late prophase- continue The chromosomes are continuing to straighten out

11. Metaphase The spindle fibers pull the chromosomes into a line across the middle of the cell

12. Metaphase- continue The chromosomes are starting to be pulled apart at the centromere The spindle fibers are starting to retract

13. Metaphase- continue The centromere is close to breaking The spindle fibers continue to retract

14. Anaphase Spindle fibers are continuing to retract and pull back towards the centrioles Chromosomes break apart at the centromere and the sister chromatids are pull toward opposite poles of the cell

15. Anaphase- continue Spindle fibers are retracting Sister chromatids are starting to pull away from the spindle fibers The cell starting to get ready to divide

16. Anaphase- continue Sister chromatids detach from the spindle fibers and come together with their partners Nuclear membrane starts to form around each set of sister chromatids Spindle fibers are almost completely retracted into the centriole

17. Telophase Set of chromosomes at each end of the cell The nucleolus reappears within each nucleus A nuclear membrane forms around the chromosomes Spindle fibers disappear The cell is now ready to divide

18. Telophase- continue The chromosomes are starting to uncoil into chromatin The cell is getting closer and closer to division

19. Telophase- continue The chromosomes uncoil further and are now almost entirely in the chromatin state The cell membrane is getting stronger and more complete The cell is ready to split in two

20. Cytokenesis Two nuclei are moved into two daughter cells Chromosomes have returned entirely to the state of chromatin The two new cells are identical to the original one The two new cells are ready to go through the life cycle again! Complete cell membrane

21. Bibliography http://ineedmoving.com/siteadmin/interphase-cell-diagram http://www.macroevolution.net/prophase-i.html http://www.phschool.com/science/biology_place/biocoach/meiosis/teloi.html http://morganterhune3a.edublogs.org/2011/11/14/cell-cycle-sequencing/ http://www.flickr.com/photos/26457459@N02/3264922970/ http://seximexibio3.blogspot.ca/ http://s322991969.websitehome.co.uk/wsb5822978901/interphase-labeled- diagram http://s322991969.websitehome.co.uk/wsb5822978901/interphase-labeled- diagram http://www.ied.edu.hk/biotech/eng/classrm/class_gene2.html