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Paraxial and Intermediate Mesoderm Formation of Somites Muscle and bone formation Intermediate mesoderm: Kidney formation.

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Presentation on theme: "Paraxial and Intermediate Mesoderm Formation of Somites Muscle and bone formation Intermediate mesoderm: Kidney formation."— Presentation transcript:

1 Paraxial and Intermediate Mesoderm Formation of Somites Muscle and bone formation Intermediate mesoderm: Kidney formation

2 Trunk Mesoderm

3 Mesoderm fate during Gastrulation/Neurulation

4 Somite Formation Periodicity Fissure formation Epithelialization specification

5 Somite Formation: Periodicity Notch and Wnt Signaling pathways In chick embryos, new somite every 90 min.

6 Somite Formation: Periodicity

7 Somite Formation: Notch Signaling

8

9 Somite Formation: Separation

10 Epithelialization of Somites Ectodermal Signal: MET Cdc42 downregulated; N-cadherin upregulated

11 Somite specification

12 Somite Differentiation

13

14 Specification Patterning of Somites

15 Building muscle

16 Building Bone Neural Crest Cells- Intramembranous ossification Endochondrial ossification

17 Vertebrae Formation

18 Dorsal Aorta Formation

19 The Syndetome: Tendon Formation

20 Intermediate Mesoderm: Kidney Formation

21 Kidney Formation Induction between Paraxial and Intermediate Mesoderm.

22 Kidney Formation: Reciprocal Induction

23 GDNF and Kidney formation

24 Who else? Wnt!

25 Development of Bladder and ducts

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