1. PDQ-Evidence

2. What is PDQ-Evidence? PDQ (“pretty darn quick”)-Evidence facilitates rapid access to the best available evidence for decisions about health systems and population health

3. It is a version of Epistemonikos database for Health systems and population health evidence

4. Epistemonikos is a non-for-profit organisation based in Santiago, Chile Our mission is “to bring high quality information closer to health decision making through the use of information technologies”

5. What evidence? Systematic reviews Overviews of reviews High-quality structured summaries Primary studies included in systematic reviews

6. The problem: information overload

7. The challenge: to separate the wheat from the chaff 23,000,000 records only in PubMed 0,25% are systematic reviews

8. Our goal TO AGGREGATE ALL THE RELEVANT HEALTH EVIDENCE (FOR DECISION-MAKING IN HEALTH SYSTEMS AND POPULATION HEALTH) INTO A SINGLE DATABASE.

9. A little bit more about PDQ-Evidence: Search strategy PDQ-Evidence was developed and is maintained by systematically searching PubMed and other databases for relevant systematic reviews and overviews of reviews. PubMed

10. Where do we search Cochrane database of systematic reviews (CDSR) Database of Abstracts of Reviews of Effectiveness (DARE) Health Technology Assessment Database PubMed LILACS SUPPORT Summaries EPPI-Centre Evidence Library 3ie Systematic Reviews and Policy Briefs WHO Database Campbell Library SURE policy briefs European Observatory on Health Systems and Policies DFID NICE public health guidelines and systematic reviews Guide to Community Preventive Services CADTH Rx for Change McMaster Plus KT+ McMaster Health Forum Evidence Briefs

11. Systematic reviews (SR) at the centre The average SR takes about 1-year of work We rescue that effort by storing identified studies From: http://www.navigatingeffectivetreatments.org.au/understanding_systematic_reviews.html The Centre for Health Communication and Participation with support from the Australasian Cochrane Centrehttp://www.navigatingeffectivetreatments.org.au/understanding_systematic_reviews.html

12. Where do we search?  20 databases

13. Systematic reviews (SR) at the centre The average SR takes about 1-year of work We rescue that effort by storing identified studies From: http://www.navigatingeffectivetreatments.org.au/understanding_systematic_reviews.html The Centre for Health Communication and Participation with support from the Australasian Cochrane Centrehttp://www.navigatingeffectivetreatments.org.au/understanding_systematic_reviews.html

14. All that effort into a single database

15. Where do we search?  20 databases

16. Relations are stored in the database

17. Unique feature One of PDQ-Evidence unique features is that it connects systematic reviews and their included studies. This makes possible to navigate between primary studies and reviews

18. Multilingual Spanish Portuguese French

19. Filters

20. Advanced search For systematic searches E.g. systematic reviews

21. Grey literature / unpublished Our search process implies searching for published literature And then going to: - the list of studies included in reviews - the list of reviews included in overviews and policy briefs INDEPENDENT OF - WHERE IS PUBLISHED (OR IF IT IS PUBLISHED AT ALL) - LANGUAGE

22. Unique feature: matrix of evidence One of PDQ-Evidence unique features is that it connects systematic reviews and their included studies. This makes possible to navigate between primary studies and reviews, but also allows clustering systematic reviews based on the primary studies they have in common. The concept of ‘Systematic reviews sharing included studies’ is a proxy of ‘systematic reviews answering a similar question’

23. Matrix of evidence

24. How do we feed PDQ-Evidence? Combination of machine technology and human collaboration ~ 10 Software engineers (for 5 years) ~ 400 collaborators (Epistemonikos)

25. Automatic search and upload Selection of actual systematic reviews by a network of collaborators Extraction of the studies included in the systematic review 1 2 3

26. The numbers 30,000 records 3,300 systematic reviews

27. Conclusions One-stop shop for evidence Multilingual database User friendly Relation between articles answering a similar question Visualisation of ‘all the evidence’ for a specific question

28. Let’ see some examples

29. Many thanks!! Contact us: contact@epistemonikos.org radagabriel@epistemonikos.org …or follow us in your preferred language: English: @epistemonikos Spanish: @epistemonikosEs German: @epistemonikosDe French: @epistemonikosFr ….also in Facebook and google+ Portuguese: @epistemonikosPt Italian: @epistemonikosIt Arabic: @epistemonikosAr Dutch: @epistemonikosNl Chinese: @epistemonikosZh

30. Gabriel Rada Associate Professor, Department of Internal Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile Director of the Evidence-Based Healthcare Program (Chilean Cochrane Centre), Pontificia Universidad Católica de Chile, Santiago, Chile Co-director of the Southern American Branch of the Iberoamerican Cochrane Centre Member of GRADE working group Co-founder, President and CEO of Epistemonikos Foundation More details here: about.me e-mail: radagabriel@gmail.com Twitter: @radagabrielabout.meradagabriel@gmail.com