1. Andrea Castañeda, Daniel Miranda, Jennifer Wang, Kevin Yeroushalmi, Joseph Youssef Course Advisors: Gordana Vunjak-Novakovic, Keith Yeager, Aaron Kyle, Sarindr Bhumiratana, Matthew Bouchard Project Advisor: Professor Clark Hung Consultants: Professor Gerard Ateshian, Professor David Vallancourt, Yukkee Cheung

2.  Background  Current status of design  Tremor detection system  Dampening system  Demonstration of functionality  Testing data  Next steps

3.  5.5 million Americans suffer from intention tremors, which affect their ability to perform daily activities  Our design targets the area of the arm which is most affected by these tremors  Our device counteracts these tremors by counteracting unwanted motion in the arm and wrist

4.  Regulatory Pathways  Relatively unhindered by regulatory committees  No FDA or Pre-Market Approval (PMA)  IRB approval  Sales Strategy  Online Retail  30 Day Money Back Guarantee  Warranty/Servicing  Retail Price: $1000

5.  Transcutaneous Electrical Nerve Stimulator (TENS)-- 60 mA, 4-6 Hz settings simulate intention tremors  5-7 lbs of dampening force counteract induced tremors at frequencies of 4-6 Hz

6. Tremor Detection  TENS  Accelerometer  Microcontroller  Defined parameters

8. Motion Dampening  Rotary damper  Acrylic moment arms  Wrist brace  Straps

10.  Arm forces

11. TENS + Elbow Brace TENS Control TENS + Elbow & Wrist Brace TENS + Wrist Brace

12. Identified ProblemsProposed Solutions Arm shifts within bulky attachmentNarrower bars/more rigid restraints shaped like arm Detection not incorporated into dampener Finalize electronic circuit Static hingeFabricate central axel and assemble dynamic hinge Current TENS setup may not accurately represent a tremor More leads or more accurate placement of leads

13. Detection Dampening Assembly Automatic vs. Manual Deactivation Form Fitting Ergonomics Compact Circuitry Finalize Electronics April 29th Final Product

14. Dampening Clutch Design Rotary damper Gear Solenoid

15. Detection Dampening Assembly Automatic vs. Manual Deactivation Form Fitting Ergonomics Compact Circuitry Finalize Electronics April 29th Final Product

16. Possible IssuesPossible Solutions Velcro allows for shiftingAdjustable straps and anatomically molded pieces Accelerometer inaccuracyMagnetic encoder OverdampeningHinge with lower torque rating Solenoid/clutch mechanism does not lock Explore other actuation options

17.  Detection system senses tremors  Mechanical system dampens up to ~50%  Integration of detection mechanism will allow for dynamic dampening  Consolidation of parts will yield ergonomic device

18.  Course Advisors  Gordana Vunjak- Novakovic, PhD  Aaron Kyle, PhD  Keith Yeager, MS  Matthew Bouchard  Sarindr Ick Bhumiratana  Project Advisor  Clark Hung, PhD  Consultants  Gerard Ateshian, PhD  David Vallancourt, PhD  Yukkee Cheung