1. Y Didi Surcel Cluj-Napoca Public Health Institute Priorities of the prevention politics regarding occupational carcinogens risks in Romania

2. THE AIM OF THIS STUDY  TO EVALUATE THE EXTENSION OF THE OCCUPATIONAL CARCINOGEN RISK IN ROMANIA  TO PROPOSE A NATIONAL SYSTEM FOR MONITORIG OCCUPATIONAL EXPOSURE TO CARCINOGENS  TO PROPOSE A NATIONAL REGISTER WITH INFORMATION ON BOTH WORK PLACES AND WORKERS EXPOSED TO CARCINOGENS  TO STIMULATE PREVENTIVE MEASURES

3. GLOBAL OBIECTIVES IMPOVEMENT OF THE EFFCIENCY OF THE ROMANIAN SYSTEM FOR OCCUPATIONAL HEALTH SURVEILLANCE IN CARCINOGEN EXPOSURE ROMANIAN ALIGNEMENT IN THIS AREA TO THE HIGH STANDARDS REQUESTED BY THE UE LEGISLATION

4. PRINCIPAL OBIECTIVES  IDENTIFICATION 0F THE OCCUPATIONAL CARCINOGENS RISKS  CARACTERISATION OF THE WORKPLACES WITH CARCINOGENIC RISK FACTORS  EVALUATE OF THE OCCUPATIONAL HAZARD WITH CARCINOGENIC POTENTIAL  MONITORING OF THE WORKPLACES WITH CARCINOGEN RISK FACTORS  BIOLOGICAL MONITORING OF THE EXPOSED WORKERS  HEALTH ASSESSMENT RELATED TO CARCINOGENS  RISK COMUNICATION  ELABORATION OF THR PLAN WITH PREVENTIVE MEASURES

5. 0UTLINE OF THE STUDY IN OCCUPATIONAL EXPOSURE TO CARCINOGENS EXPOSURE MONITORING EVALUATION OF THE HEALTH STATUS Measurement of the chemical concentr. in the workplace air Measurement of the chemical concentr. or its metabolite in biological sample colected from the workers GEN. MEDIC. EXAM. STANDARD QUESTION. PARACLI NICAL EXAM. LAB. EXAM - overlooking the workers health in connection with carcinogens exposure - preventive measureas in workplace

6. DETECTION OF THE OCCUPATIONAL EXPOSURE TO CARCINOGENETIC ELECTROPHILIC COMPOUNDS ELECTROPHILIC COMPOUNDS monooxygenase glutathione S- transferase Intermediate reactant NONTOXIC METABOLITE COVALENT BINDING URINARY THYOETHERS CHEMICAL DESTRUCTION OF TARGET MOLECULES CYTOGENETIC ANORMALITIES chromosome gaps micronuclei