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with slides borrowed from
Portal MR Venography with slides borrowed from Tom Grist, MD Jorg Debatin, MD Qian Dong, MD Ruth Carlos, MD David Stafford-Johnson, MD Mohammed Neimatallah, MD Brian Hamilton, MD Jochen Gaa, MD
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Arterial phase Portal venous phase 1
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Coronal 3D Gd MRA of Portal Vein
Coronal Plane Field of view = width of patient (28-32 cm) Thick slices: 3-5 mm Zero padding Fast enough for breath holding TR < 10 msec TE < 3 msec Partial Fourier imaging (0.5 NEX) Adjust phase encoding steps ( ) Three phases Arterial Portal venous Equilibrium
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Mesenteric Portal Protocol
Sequence Time Sag SSFSE 0:56 Axial T1 5:32 Axial T2 & fat sat 6:04 MRCP (optional) Coronal 3D Gd (3 phases) 0:30 x 3 Axial 2D TOF (optional) Total imaging time ~15-25 minutes
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Arterial Phase Venous Phase
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Hepatoma Venous Phase
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Fig Hepatoma. Clinical Scenario: 54-year-old female with abdominal pain and elevated AFP. Technique: Coronal Acquisition, TR/TE/Flip = 8.1/2.1/45°, Field-of-View = 320 x 320 x 96 mm, Matrix 256 x 160 x 32, Centric Ordering of k-space, Acquisition Time = 29 s, 40 ml gadolinium contrast infused at 2 ml/s, and timed empirically. Interpretation: A coronal MIP from the portal venous-phase of the contrast bolus shows an enhancing mass in the dome of the liver with heterogenously enhancing tumor invading the right portal vein and extending down to the confluence of right and left portal veins. The main and left portal veins are widely patent. Diagnosis: Hepatoma with invasion of right portal vein. Submitted by Martin R. Prince, M.D., Ph.D., Ann Arbor, MI. 7
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Sub-Volume MIP MIP of Entire 3D Volume Axial Reformation
Main Portal Vein SMV Main Portal Vein Axial Reformation
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Sub-Volume MIP MIP of Entire 3D Volume Axial Reformation
Right Hepatic vein Right Hepatic vein Axial Reformation
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Portal hypertension with varices
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Coronal 3D Gd MRA MIP during venous phase
55 year old female prior to TIPS Coronal 3D Gd MRA MIP during venous phase
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Varices Thick MIP Thin MIP
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Portal hypertension
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Spleno-renal shunt Anterior MIP Posterior MIP
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3 Fig. 7.3. MRA of Portocaval Shunt.
Clinical Scenario: 42-year-old male, status post-portocaval shunt with worsening ascites. Technique: Coronal Acquisition, TR/TE/Flip = 7.2/1.2/45°, Field-of-View = 300 x 300, Matrix = 256 x 128, Centric Ordering of k-space, Acquisition Time = 32 s, 1 NEX, 40 ml of gadolinium infused at 2 ml/s, and timed empirically. Interpretation: Coronal subvolume MIP (a) and magnification view (b) shows a widely patent portocaval shunt (arrows). Note also gastric varices (arrowheads). During this equilibrium phase image, there is comparable enhancement of the portal vein, IVC, and aorta. Diagnosis: Patent portocaval shunt. Submitted by David Stafford-Johnson, M.D., Ann Arbor, MI. Reprinted with permission from Investigative Radiology Sept. Oct 3
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56 year old female with abdominal pain
Minimun intensity projections Maximum intensity projection
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Portal and hepatic vein thrombosus
Minimun intensity projections Maximum intensity projection
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Acute thrombosis of portal vein (arrows) with perithrombus enhancement (arrowheads)
Maximum Intensity Projection 6
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Cavernous Transformation
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32-year-old female with abdominal pain
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Budd Chiari
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Fig Liver Transplant. Clinical Scenario: Status post liver transplant with increased liver function tests. Technique: Coronal Acquisition, TR/TE/Flip = 7/2.1/45°, Field-of-View = 320 x 320 x 84 mm, Matrix = 256 x 128 x 28, Sequential Ordering of k-space, Acquisition Time = 27 s, 40 ml gadolinium contrast infused at 2 ml/ s, and timed empirically. Interpretation: Coronal oblique subvolume MIP shows a widely patent splenic and portal veins. There is minor narrowing (arrows) at the site of anastomosis between the native and donor portal veins. Diagnosis: Widely patent transplant portal vein. Submitted by Martin R. Prince, M.D., Ph.D., Ann Arbor, MI. v 4
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IVC anastomotic narrowing
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13 year old female post liver and kidney transplant
Arterial Phase Portal-venous Phase
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Post Liver Transplant
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Post Liver Transplant with
abcess narrowing portal vein
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Pancreatic mass encasing celiac and spleno-portal confluence
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Summary Normal flow: Gd not necessary Slow flow: Gd essential
Coronal 3D: thick slices & breathholding Useful for evaluating Varices Shunts Tumor encasement Tumor invasion Thrombosis Cavernous transformation Budd Chiari Liver transplant
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