1. ERYTHROPOEISIS RBC Basophilic Polychroma- Orthochroma- Hemocytoblast
Proerythroblast
Erythroblast
tophilic
tophilic
Nuclear
Reticulocyte
Erythroblast
Erythroblast
Extrusion
1. dispersed
1. clumped
1. condensed
1. condensed
1. anucleate
Pluripotential
chromatin
eccentric
chromatin
chromatin
Stem Cell
nucleus
2. spherical
2. grey-green
2. nucleoli
2. no
2. pink
cytoplasm
3. slight
nucleoli
cytoplasm
basophilia
(hemoglobin
3. cytoplasmic
3. maximum
(free ribosomes)
synthesis)
basophilia
basophilia

2. Erythropoeisis- Several Stages

3. MYELOPOEISIS Hemocytoblast Myeloblast Promyelocyte (granulopoeisis)
(multipotential)
(multipotential)
Promyelocyte
(multipotential)
1. loss of cytoplasmic
basophilia
2. dispersed chromatin
Eosinophilopoeisis
Neutrophilopoeisis
Basophilopoeisis

4. EOSINOPHILOPOEISIS Eosinophilic Eosinophilic Eosinophil Myelocyte
Metamyelocyte
(band cell)
Specific and
Metachromatic Granules

5. Eosinophilopoeisis- Several Stages

6. NEUTROPHILOPOEISIS NEUTROPHILIC NEUTROPHILIC MYELOCYTE METAMYELOCYTE

7. MYELOPOEISIS (Several Stages)
Nutrophilic Band and
Neutrophilic and Eosinophilic Band Cells
Eosinophilic Metamyelocyte

8. BASOPHILOPOEISIS Basophilic Basophilic Myelocyte Basophil
Metamyelocyte

9. THROMBOPOEISIS Endomytosis Reserve Megakaryocyte (megakaryoblast)
(w/o karyokinesis
Hemocytoblast
(w/o cytokinesis)
Reserve Megakaryocyte (megakaryoblast)
Platelet-Forming Megakaryocyte
Residual Megakaryocyte
Platelet-Shedding
Platelets
(fusion of
plasma membrane)

10. MEGAKARYOCYTES

11. BONE MARROW
Decalcified Bone and
Marrow
Marrow Cavity
Fat Cells
Bone

12. Marrow Endothelial Cells Megakaryocyte Diapedesis Adipocyte
Discontinuity
Blood
Sinusoid
Reticular
Hemopoetic
Fibers
Compartment

13. Bone Marrow
Bone Marrow in Decalcified Bone
Bone Marrow Smear