1. Opener: What controls all cell activities and determines our features?

2. Alfred Hershey and Martha Chase’s experiment
Section 12-1
Bacteriophage with phosphorus-32 in DNA
Phage infects bacterium
Radioactivity inside bacterium
Bacteriophage with sulfur-35 in protein coat
Phage infects bacterium
No radioactivity inside bacterium
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3. Hershey-Chase Experiment
Section 12-1
Bacteriophage with phosphorus-32 in DNA
Phage infects bacterium
Radioactivity inside bacterium
Bacteriophage with sulfur-35 in protein coat
Phage infects bacterium
No radioactivity inside bacterium
Go to Section:

4. Hershey-Chase Experiment
Section 12-1
Bacteriophage with phosphorus-32 in DNA
Phage infects bacterium
Radioactivity inside bacterium
Bacteriophage with sulfur-35 in protein coat
Phage infects bacterium
No radioactivity inside bacterium
Go to Section:

5. Rosalyn Franklin
Her work was used by James Watson and Francis Crick to figure out the structure of DNA

6. Percentage of Bases in Four Organisms
Section 12-1
Percentage of Bases in Four Organisms
Source of DNA A T G C
Streptococcus
Yeast
Herring
Human
Chargaff’s Rule!
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7. James Watson
and
Francis Crick

8. DNA Nucleotides Purines Pyrimidines Section 12-1 Phosphate group
Adenine
Guanine
Cytosine
Thymine
Phosphate group
Deoxyribose
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9. Structure of DNA Nucleotide Hydrogen bonds Sugar-phosphate backbone
Section 12-1
Nucleotide
Hydrogen bonds
Sugar-phosphate backbone
Key
Adenine (A)
Thymine (T)
Cytosine (C)
Guanine (G)
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10. DNA Replication Section 12-2 Go to Section: Original strand
DNA polymerase
New strand
Growth
DNA polymerase
Growth
Replication fork
Replication fork
Nitrogenous bases
New strand
Original strand
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11. THE DNA SONG!! To the tune of “Row, row your boat”
We love DNA Made of nucleotides. Sugar, phosphate and a base Bonded down one side.
Adenine and thymine Make a lovely pair. Cytosine without guanine Would feel very bare.