1. Case 10

2. Basic clinical and pathological data 49-year-old male Prostatic symptomatology Increased level of PSA (up to 6 ng/ml) Prostate 35 g 4x 4 x 3 cm

3. ???

4. Grey squirrel

5. Our diagnosis Nephrogenic „adenoma“

6. 60% past surgery Association with trauma, calculi or renal transplantation 2/3 are males, 1/3 are younger than 30 years of age 80% in urinary bladder, less frequently in ureters and urethra, or in renal pelvis Macroscopicaly usually polypoid or sessile, friable mass

7. Differential dg: NA vs Adenoca+TCC

8. Differential dg: NA vs Clear cell (mesonephric) adenoca

9. Adenoca in situ Adenoca

10. Differential diagnosis- depends also on localisation Adenocarcinoma or TCC with adenocarcinomatous component collecting duct RCC in renal pelvis Urothelial CIS, particularly in initial stage