1. LOWER SHORE TECHNOLOGY TRANSFER SYMPOSIUM Bringing the Benefits of Discovery to the World MAY 23, 2012 Wesley D. Blakeslee Executive Director Johns Hopkins Technology Transfer 410-516-8300 wdb@jhu.edu

2. JHTT Mission Statement The Johns Hopkins Technology Transfer office furthers the mission of The Johns Hopkins University to bring the benefits of discovery to the world, by implementing the commercialization of University innovations for the public good by: Encouraging and supporting invention disclosure; Encouraging and supporting entrepreneurs; Effecting technology development and licensing; Increasing available research funding; and Protecting and managing the University's intellectual property 2

3. Large Experienced Office 50+ employees, including: – Experienced Senior Management – 12 Experienced Licensing Professionals – 5 IP Managers – 3 Patent Attorneys – 4 Agreements Specialists – 2 Marketing And Corporate Relations Managers – 1 Dedicated New Ventures Manager – Experienced Support Staff 3

4. Faculty Service - Our #1 Goal Electronic submission, staff assistance Patent search, marketing research, broad-based marketing Disclosures Industry – University relations Startup company guidance Business Development Invoicing and collections Quarterly royalty distributions Financial Online faculty system access (transparency) Faculty and departmental reporting Information Improving turnaround with greater volume New electronic solutions Material Transfers 4

5. Finding Technology Publications Conferences Inventor JHTT JHTT Events JHTT Outreach JHTT Website 5

6. JHTT Contact the office – Contact info on website – Hotline: –JHTT-Communications@jhu.eduJHTT-Communications@jhu.edu Sign up for alerts 6

7. JHTT Events Programming – Alliance for Science and Technology – Annual Bioinvestor Conference – Special events – “Vine and Venture” Match Making Service – Represent smaller spin-offs at large networking/partnering events 7

8. JHTT Outreach – Licensing – Approximately 2,000 technologies available – Sponsored Research – Solve exquisitely difficult problems – Industry Experts – For consulting or scientific advisory boards – More than 80 JHU start-up companies in various stages of development – Clinical trials 8

9. Technology Commercialization Company Formation and Entrepreneurial Development Programs Vine & Venture Forum Annual Biotech Investor Conference Biotech and Medical Conferences Entrepreneurial Medical Device Tool Kit Day BioMatch Entrepreneurial Speed Dating Innovative Marketing

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11. Make the Connections Biomatch – A dozen inventors “speed date” with a dozen entrepreneurs – Determine the best match for longer discussion Regional / National Events – J.P. Morgan SF Healthcare Conference – Sponsor start-up attendance at important regional meetings 11

12. JHTT Website Fully Searchable database Boolean, flexible Google and other search engine available http://www.techtransfer.jhu.edu/ – click “Search Available Technologies Contact licensing associate 12

13. Johns Hopkins Technology Transfer: There’s an app for that! NOW AVAILABLE! Download from App store

14. Deal Process Deal Terms Engage the assigned Licensing Associate Discuss deal terms Exchange term sheet Agree on deal terms 14

15. Deal Process Agreement Receive JHTT standard license agreement with agreed terms Negotiate minor changes to JHTT Standard Agreement Sign and Drive 15

16. Technology Value Curve MARKET EXPANSION COMMERCIAL LAUNCH PROTOTYPE/ CLINICAL TRIAL PROOF OF CONCEPT IDEA Commercialization Stage 16

17. Common Deal Terms – Required provisions Each deal depends on many factors Required provisions Licensee covers patent costs JHTT Controls prosecution Licensee Indemnifies JHU Sublicensing consideration 17

18. Common Deal Terms – Typical Provisions Typical Provisions: Up front licensing fee Annual fee/Minimum Annual Royalty Milestone Payments Patent Issuance IND Clinical Trials Regulatory Approval First commercial sale, and sales milestones Running royalty on sales 18

19. Startups Since This Century Began (1/1/2000): – 66 JHU Startups – Startups received >$476 M in funding – FY08 record funding year – >$76 Million funding to 12 startups – FY11 record number year – 19 new ventures Director of Ventures 19

20. Startup Deal Terms Startup deals can differ substantially from established companies Cash is king, startups have little Often need to defer costs Rules, however, prohibit funding startup expenses Patent costs already incurred can be deferred New costs must be paid when incurred 20

21. Be creative Equity Change of control premium Low cost up front and annually Payments on value inflection Sublicense and cash out fees Startup Deal Terms 21

22. Tech Transfer Dilemma $$$ Not necessarily priority of faculty But important to University Happy FacultyHappy Financial Folks 22

23. Who Will Be The Best Partner? Most likely to bring a good product to market Best relationship with the University and faculty member 23

24. Other Options For Working With Technology/Inventors – JHTT is the Hopkins business concierge providing personalized service into JHU business 24

25. Industry – Faculty Relations Consulting Collaborative Research Joint Development Sponsored Research 25

26. LOWER SHORE TECHNOLOGY TRANSFER SYMPOSIUM Bringing the Benefits of Discovery to the World MAY 23, 2012 Wesley D. Blakeslee Executive Director Johns Hopkins Technology Transfer 410-516-8300 wdb@jhu.edu Questions?