1. HEALTH Caffeine Timothy Valentine

2. Table of Context Part 1 4.Definition 5.Effects 6.Usage 7.Stats 8.History 9. Heart Effects 10.Brain Effects 11.Liver Effects 12.Long Term 13.Side Effects 14.Intoxication 15.Tolerance 16.Interactions

3. Table of Context Part 1 17.Addiction 18.Withdrawl 19.Overdose 20.Death 21.Bibliography

4. What is Caffeine? “C pill” “Coffee”Coffee “Wake Ups” “Vivarin” Stimulant-A substance that raises levels of physiological or nervous activity in the body.

5. Caffeine Effects Decreases depression Increases stamina Increases heart rate Decreases boredom Seriously….

6. Caffeine Administration and Onset Typically ingested Sometimes transdermally Takes 5-10 minutes Duration: 1.5-5 hours After effects last up to 24 hours

7. Caffeine Statistics 32% say they are dependent on caffeine 80-90% of Americans consume caffeine on a regular basis Tampa is the most caffeinated city in the US

8. History Stone Age- berries with caffeine 2700BC- Chinese drink tea The Mayans drank spicy cacao 900AD Ethiopian herders eat coffee beans 1600 Coffee in Europe 1767 Coffee replaces tea in colonies (Townsend revenue act) 1909 caffeine reduced in Coca Cola (40 barrels and 20 kegs)

9. HEART! Increases Blood pressure May cause Arrhythmia May cause Tachycardia

10. BRAIN! Causes the release of Dopamine Causes the release of Adrenaline Limits Adenosine which causes alertness Causes the release of cortisone which constricts blood cells (high BP)

11. LIVER! Creates caffeine hydrochloride (toxin) Bile flushes it out Regularity

12. Long Term Effects Dehydration Decreases change of Parkinson’s Suppresses Hepatitis Increases chance of cancer Increases blood pressure

13. Side Effects/ Allergies More acute and more frequent PMS Panic Attacks Typical Allergy Reactions Hives Swelling Etc

14. Intoxication 300 mg a daily over stimulates the nervous system Anxiety Flushed face Twitching Tachycardia

15. Tolerance High Doses (750-1200 mg) for 18 days leads to complete tolerance sometimes 400 mg for 7 days can cause complete tolerance Amounts under 400 mg cause partial tolerance

16. Drug Interaction Increases the strength of analgesics Increases strength by 40% Increases speed of processing

17. Addiction Currently my status Can occur with just 100 mg a day Forms a physical dependence

18. Withdrawal symptoms Headaches Muscle pains Stiffness Lethargy Nausea Irritability Depression

19. Caffeine Overdose Panic attacks Arrhythmia Vomiting Myocardial Infarction (big word)

20. DEATH A 50% chance (LD50) id 192 mg per kg of weight That’s about 2-20 grams Which is Unlikely Don’t Try it

21. Bibliography http://www.caffeinedependence.org/caffein e_dependence.html http://www.caffeinedependence.org/caffein e_dependence.html http://www.life123.com/health/nutrition/caffe ine/history-of-caffeine.shtml http://www.life123.com/health/nutrition/caffe ine/history-of-caffeine.shtml http://www.acnp.org/g4/gn401000165/CH1 61.html http://www.acnp.org/g4/gn401000165/CH1 61.html http://www.erowid.org/chemicals/caffeine/