Download presentation
Presentation is loading. Please wait.
1
PBS 10 mg/kg paracetamol 50 mg/kg paracetamol 100 mg/kg paracetamol 200 mg/kg paracetamol PBS 10 mg/kg caffeine 10 mg/kg paracetamol + 10 mg/kg caffeine 50 mg/kg paracetamol + 10 mg/kg caffeine 100 mg/kg paracetamol + 10 mg/kg caffeine 200 mg/kg paracetamol + 10 mg/kg caffeine PBS Paracetamol 10 mg/kg caffeine Paracetamol + 10 mg/kg caffeine 5 Response Latency (s) * 0 1 2 3 4 -10 153045 * * * * * * * * * (A) Time (min) * * (B) 0 1 2 3 4 5 -101530 45 Response Latency (s) 5 # # # * (C) Dose of paracetamol (mg/kg) 0 1 2 3 4 0 10100 1000 Response Latency (s)
2
PBS 50mg/kg paracetamol 3mg/kg SCH58261 50mg/kg paracetamol + 3mg/kg SCH58261
3
PBS 10 mg/kg paracetamol 20 mg/kg paracetamol 50 mg/kg paracetamol 100 mg/kg paracetamol 200 mg/kg paracetamol PBS 10 mg/kg caffeine 50 mg/kg paracetamol + 10 mg/kg caffeine 100 mg/kg paracetamol + 10 mg/kg caffeine 200 mg/kg paracetamol + 10 mg/kg caffeine PBS Paracetamol 10 mg/kg caffeine Paracetamol + 10 mg/kg caffeine Response Latency (s) * * * * * * * (B) 0 5 10 15 20 -10 153045 Time (min) Response Latency (s) * * * * * (A) 0 5 10 15 20 -10153045 Time (min) * * * * * * * # Dose of paracetamol (mg/kg) 0 5 10 15 20 0 101001000 (C)
Similar presentations
