1. Plan for the coming years VELUX FONDEN - D A N I S H A G I N G R E S E A R C H C E N T E R - www.sdu.dk/darc Why do we age so differently?

2. General plans  To finalize Copenhagen Aging and Midlife Biobank (CAMB)  2010 The Metropolit Part of CAMB finalized  2011 All data on CAMB have been collected,documented and made ready for analyses  2011 Data from CAMB has been linked to relevant registers  To develop plans for DARC-projects using data from CAMB  To develop collaborative studies between Center for Healthy Aging and DARC

3. New projects on early aging signs - DARC  Association between unexplained fatigue and biomarkers  How does mitochondrial function relate to unexplained fatigue? (extension of ongoing study –Copenhagen – Aarhus)  Association between social class and biomarkers  How does mitochondrial function relate to social class? (extension of ongoing study –Copenhagen – Aarhus)  New study on the relations between unexplained fatigue and oxidative stress in midlife  Collaboration between CESA, CAMB and DARC  (V. Bohr, T. Stevnsner, M.Osler, E.L.Mortensen, K.Avlund)  Using data from CAMB (outliers on fatigue)

4. Which genetic and environmental factors affect functional capacity and lifespan?  New projects in relation to A.Ekmann’s Ph.D.-study  Which health and environmental factors affect unexplained fatigue in midlife ?  How do socioeconomic position and social relations influence unexplained fatigue in midlife?

5. Socioeconomic position Familiar factors (genetics and rearing environment) Ageing (longevity, chronic disease) Sibling cohort study- linking family database-to health and social registers in Statistics Denmark New PhD-study/post doc? Social status and telomeres in a longitudinal design (MONICA cohort) How important are familial factors for social differences in lifespan?

6. Socioeconomic Position Cognitive funtion (IQ) Familiar factors (genetics and rearing environment) Ageing (cognition, longevity) Twin register and cohorts- linked to health, conscript database and social registers in Statistics Denmark How important are familial factors for social differences in lifespan?