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G ENETICS !
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G REGORY M ENDEL Born 1822; Died 1884 Monk and a teacher Work not recognized until 1900 Studied heredity by studying pea plants What is heredity?
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MENDEL’S PEA PLANTS Observed seven characteristics of pea plants with two different traits Controlled how each plant was pollinated Self-pollination or cross-pollination What’s the difference?
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MENDEL’S EXPERIMENTS Grew true-breeding plants What does it mean to be true breeding? Starting strain called parent generation or P generation P generation Cross-pollinated P generation to produce offspring called the first filial generation or F 1 generation F 1 generation F 1 generation self-pollinated and produce the second filial generation or F 2 generationF 2 generation
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x P generation
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x F 1 generation All of the F 1 showed one color
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x F 2 produced plants about ¾ one trait and ¼ the other trait P generation F 1 generation F 2 generation
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R ESULTS Factor was controlling the traits since there were two traits there were two factors Alleles : represent the factors - dominant CAPITAL LETTERS; recessive lower case letters; They are alternate forms of genes. Dominant trait : Able to repress the other trait Recessive trait : repressed by the dominant Homozygous : same alleles; RR or rr – also called purebred or true breeding Heterozygous : one of each allele forming a hybrid Rr Genotype : allele pairs/actual DNA: RR, Rr, or rr Phenotype: physical appearance; red, yellow, green, tall, short, etc. *You only see the recessive phenotype when there are two of the recessive alleles. Whenever you see the dominant phenotype, you cannot tell the genotype.* Lead to the modern study of molecular genetics, the study of chromosomes and genes. Y y
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L AWS OF G ENETICS Law of Segregation : a pair of factors is segregated or separated during the formation of gametes (i.e. the homologous chromosomes are separated during anaphase I of meiosis I into different gametes.) Law of Independent Assortment : factors for different characteristics are distributed to gametes independently – factor for different traits do not follow each other into the same gamete
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P ROBABILITY Probability that a specific event will occur; expressed as a decimal, fraction, or percent Probability = Number of times an event happened Number of possible opportunities The predicted results are more likely to occur the more trials that are performed
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M ONOHYBRID C ROSSES Monohybrid cross: between individuals with one pair of contrasting traits ( mono = one) Punnett squares are used to help predict the probability of a trait
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H OMOZYGOUS X H OMOZYGOUS Crossing two plants homozygous for color (P) One dominant one recessive PP x pp Genotype 4 Pp Phenotype 4 purple
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H OMOZYGOUS X H ETEROZYGOUS Crossing a homozygous dominant with a heterozygous plant for color (P) PP x Pp Genotype 2 PP 2 Pp Phenotype 4 purple
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H OMOZYGOUS X H ETEROZYGOUS Crossing a heterozygous plant with a homozygous recessive for color (P) Pp x pp Genotype 2 Pp 2 pp Phenotype 2 purple 2 white
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H ETEROZYGOUS X H ETEROZYGOUS Both heterozygous for color (P) Pp x Pp Genotype 1 PP 2 Pp 1 pp Phenotype 3 purple 1 white
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T ESTCROSS Used to determine the genotype of a individual with an unknown genotype Must use an organism of an known genotype hence use a homozygous recessive
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