1. 20,000 GENES IN HUMAN GENOME; WHAT WOULD HAPPEN IF ALL THESE GENES WERE EXPRESSED IN EVERY CELL IN YOUR BODY? WHAT WOULD HAPPEN IF THEY WERE EXPRESSED IN THE WRONG CELLS? WARM-UP # 5 1/13/2015

2. Why is control of gene expression important? Antennapedia

3. How do cells know which genes to use? 98% of human genome does NOT code for proteins! RNA polymerase – enzyme that produces mRNA

4. Promoter Region of DNA that begins transcription

5. TRANSCRIPTION FACTORS o Proteins that control transcription o Bind to enhancer DNA o Always present in cell, but most likely have to be activated before they will bind to DNA

6. Transcription Factors Essential for the transcription of all protein- coding genes Can either repress or enhance transcription