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Figure 10.6 Structure of the Neuromuscular Junction Process Diagrams Step-by-Step Copyright © 2007 by John Wiley & Sons, Inc.

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Presentation on theme: "Figure 10.6 Structure of the Neuromuscular Junction Process Diagrams Step-by-Step Copyright © 2007 by John Wiley & Sons, Inc."— Presentation transcript:

1 Figure 10.6 Structure of the Neuromuscular Junction Process Diagrams Step-by-Step Copyright © 2007 by John Wiley & Sons, Inc.

2 1 Axon terminal Axon collateral of somatic motor neuron Sarcolemma Myofibril ACh is released from synaptic vesicle Junctional fold Synaptic vesicle containing acetylcholine (ACh) Sarcolemma Synaptic cleft (space) Motor end plate Synaptic cleft (space) (a) Neuromuscular junction (b) Enlarged view of the neuromuscular junction (c) Binding of acetylcholine to ACh receptors in the motor end plate Synaptic end bulb Synaptic end bulb Neuromuscular junction (NMJ) Synaptic end bulb Motor end plate Nerve impulse 1

3 1 Axon terminal Axon collateral of somatic motor neuron Sarcolemma Myofibril ACh is released from synaptic vesicle ACh binds to Ach receptor Junctional fold Synaptic vesicle containing acetylcholine (ACh) Sarcolemma Synaptic cleft (space) Motor end plate Synaptic cleft (space) (a) Neuromuscular junction (b) Enlarged view of the neuromuscular junction (c) Binding of acetylcholine to ACh receptors in the motor end plate Synaptic end bulb Synaptic end bulb Neuromuscular junction (NMJ) Synaptic end bulb Motor end plate Nerve impulse Na + 1 2 2

4 1 Axon terminal Axon collateral of somatic motor neuron Sarcolemma Myofibril ACh is released from synaptic vesicle ACh binds to Ach receptor Junctional fold Synaptic vesicle containing acetylcholine (ACh) Sarcolemma Synaptic cleft (space) Motor end plate Synaptic cleft (space) (a) Neuromuscular junction (b) Enlarged view of the neuromuscular junction (c) Binding of acetylcholine to ACh receptors in the motor end plate Synaptic end bulb Synaptic end bulb Neuromuscular junction (NMJ) Synaptic end bulb Motor end plate Nerve impulse Muscle action potential is produced Na + 1 2 3 2

5 1 Axon terminal Axon collateral of somatic motor neuron Sarcolemma Myofibril ACh is released from synaptic vesicle ACh binds to Ach receptor Junctional fold Synaptic vesicle containing acetylcholine (ACh) Sarcolemma Synaptic cleft (space) Motor end plate Synaptic cleft (space) (a) Neuromuscular junction (b) Enlarged view of the neuromuscular junction (c) Binding of acetylcholine to ACh receptors in the motor end plate Synaptic end bulb Synaptic end bulb Neuromuscular junction (NMJ) Synaptic end bulb Motor end plate Nerve impulse Muscle action potential is produced ACh is broken down Na + 1 2 4 3 2


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