1. Diffractive Multifocal IOL Prof. Dr. Daniel H. Scorsetti
EYEDIFF PLUS +3.50D
Diffractive Multifocal IOL
“A New Alternative”
Prof. Dr. Daniel H. Scorsetti
University of the Salvador - Catholic Pontificia University of Argentina
Faculty of Medicine - Faculty of Medical Sciences
Chair of Ophthalmology
Buenos Aires, Argentina

2. Eyediff Plus +3.50D: Technical Specifications

3. EYEDIFF Plus Presbyopic IOL
Diffractive Technology
Perfect Light Distribution for Distance &Near( 60/40)‏
Addresses Cataract Patients with or without Presbyopia
Allowed Patients a High Level of Freedom From Glasses in clinical trial

4. Full Optic Regular Diffractive IOL
Advantages
Provides multifocal vision
Reduced pupil dependency
Balanced distribution of light
Able to tolerate some decentration

5. Full Optic Diffractive IOL
Disadvantages
Potential for Scattering of light and glare and halos at night but
Advantages
Provides multifocal vision
Reduced pupil dependency
Balanced distribution of light
Able to tolerate some decentration
* Creates Halos and scattering Light

7. Zones

8. EYEDIFF Plus - Predictable refractive outcome
+3.00D Addition

9. EYEDIFF Plus - Predictable refractive outcome
+3.50D Addition

10. EYEDIFF Plus - Predictable refractive outcome
+4.00D Addition

11. Show Optic
Far
Intermediate
Near

12. EYEDIFF PLUS – Predictable Customized LIO

13. EYEDIFF PLUS - Predictable refractive outcome
Analysis of the mistake : Square root of the sum of the squares
Warren E. Hill, MD, FACS

14. EYEDIFF PLUS - Predictable refractive outcome
Analysis of the mistake : Square root of the sum of the squares
Warren E. Hill, MD, FACS

15. Aspheric Optic (Aberration Neutral)

16. 360° Square Edge

17. EYEDIFF Plus 360⁰Square Edge
Edge thickness correspond to standard designed IOLs
Square edge design
Perfect centration in the capsular bag
Perfect optical performance
Extremely low incidence of PCO
Anti Z effect Haptic design

18. IOL Power calculation Careful Keratometry
1.0D corneal power error affects 1.3 to 1.6D IOL power calculation
Careful Axial Length
1.0mmAL error affects the post-operative refraction by 1.2 to 2.5D aprox.
IOL Master: SRK II  
SRK T  118.4
  Holladay 1 - sf
  Haigis a0=0.95, a1=0.4, a2=0.10
  Hofer - pACD
Aim Emmetropia & Astigmatism <1.0D
A-Const. & ACD ( Surgeon Factors)‏

19. Clinical Trial
Objective: to compare the visual quality preop and postop., between 2 multifocal IOLs and 1 monofocal
Material and methods : 60 eyes of 30 pts. divided into 3 groups, informed and signed assent, cataract degrees II and III, older than 55 years (average 60 years), without ocular disease or astigmatism > 1.0D. Bilateral implants, the same IOL in every patient (not mix and match)
Equipment: Alcon Infinity Technique : Facotorsional with Ozil IP, 2.2mm (intrepid) Incision in the steepest axis and the same protocol in all cases
Group 1: 10 pts. Acrysoft IQ
Group 2: 10 pts. Acrysoft Restor
Group 3: 10 pts. EYEDIFF PLUS +3.5D

20. Clinical Trial Preop Complete ocular exam:
UCVA & BCVA: far, intermediate (70 cm) and near (40 cm)
Pentacam HR
IOL Master
Contrast Sensibility : photopic and mesopic
NEI VFQ-25 Questionnaire with Apéndix NEI VFQ-39 (in Spanish)
6 questions to evaluate visual general health
20 questions to evaluate difficulties in visual activities
13 questions to evaluate level of acceptance of visual loss
NEI VFQ: National Eye Institute, Visual Function Questionnaire

21. Clinical Trial Postop complete examination : days 1 - 7- 30 - 90
UCVA & BCVA: far, intermediate (70 cm) and near (40 cm)
Pentacam HR
Contrast Sensibility : photopic and mesopic
NEI VFQ-25 Questionnaire with Apéndix NEI VFQ-39 (in Spanish)
6 questions to evaluate visual general health
20 questions to evaluate difficulties in visual activities
13 questions to evaluate level of acceptance of visual loss
Follow-up 3 months

22. Results Questionnaire
Group 2 and 3: better in postop. to read newspaper and close vision activities.
Group 3: less difficulty in night driving, But without statistically significant difference with 2.
Group1: statistical significant difference to favor to drive by night
Without intraop complications
Without PCO
Descentrations
2 minor in group 2
1 minor in group 3
Halos/Glare
3 tolerable in group 2
2 tolerable in group 3

23. Results FAR – GROUP 1: Acrysoft IQ
UCVA
BCVA

24. Results FAR – GROUP 2: Acrysoft Restor
UCVA
BCVA

25. Results FAR – GROUP 3: EYEDIFF PLUS
UCVA
BCVA

26. Results NEAR – GROUP 2: Acrysoft Restor
UCVA
BCVA

27. Results NEAR – GROUP 3: EYEDIFF PLUS
AV S/C
AV C/C

28. Intermediate Vision (70 cm)
GROUP 2
Acrysof Restor
DECIMAL
DISTANCE
INTERMEDIATE WITHOUT CORRECTION
0.4
70 cm
INTERMEDIATE WITH CORRECTION
1.0
GROUP 3 –
EYEDIFF PLUS
DECIMAL
DISTANCE
INTERMEDIATE WITHOUT CORRECTION
0.5
70 cm
INTERMEDIATE WITH CORRECTION
1.0

29. EYEDIFF Plus

30. EYEDIFF Plus

31. Conclusions Less adverse effects Good results post-surgery
Individual map with MTF and topography of IOL power
Variety of powers for near
First Customized IOL
Cost

32. Thank you very much!!!