1. 病原生物学 Medical Microbiology and Parasitology Part I: Medical Microbiology Part II: Medical Parasitology

2. Medical Microbiology Xiao-Kui GUO( 郭晓奎） Dept. of medical Microbiology and Parasitology E.mail: xkguo@shsmu.edu.cnxkguo@shsmu.edu.cn Tel: 776712 Office: 5-511

3. Introduction  Microorganisms(Microbes)  Microbiology  Medical Microbiology

7. What is Microorganisms  Microorganisms are creatures that are not directly visible to the unaided eye, with dramatical biologic diversity.  Viruses, bacteria, fungi, protozoa and some algae are all in this category  All with the exception of plants and animals

9. Distribution of microorganisms  Air  Soil  Water  Animals  Human body

11. 100m 300m 1400m 2100m 3150m 4050m 6000m

12. Microorganisms and Human Beings  Beneficial activities: Most microbes are of benefit to human beings, some are necessary( nitrogen, carbon cycles, etc)  Harmful activities: A portion of microbes cause diseases and are poisonous to human, and these are really that concern us in the study of medical microbiology, etc.

15. Microbiology  Microbiology is the biology of microorganisms. It is a bioscience for the study of the evolution, Classification, morphology, physiology, genetics, ecology of microbes under certain definite conditions, The law of their life activities, and their interaction with human being, animals or plants as well as with natural environment.

16. The Importance of Microbiology  Environment  Medicine  Food  Industry  Biotechnology  Research

17. History of Microbiology  Experience phase 经验时期  Experimental phase 实验时期  Modern phase 现代微生物学时期

18. Experience phase

19. Experimental phase  Leeuwenhoek  Pastur  Koch  Lister

25. Koch’s postulates  The microbe must be found in the body in all cases of the disease  It must be isolated from a case and grown in a series of pure culture in vitro  It reproduce the disease on the inoculation of a late pure culture into a susceptible animal  The microbe must be isolated again into pure culture from such experimentally caused infection.

27. 艾利希， 1910

32. Modern phase

33. Fei-Fan Tang

34. Emerging and Reemerging Infectious Disease  AIDS  Tuberculosis  Hepatitis  Gastric ulcer  SRAS

35. Medical Microbiology  The medical microbiology is one of the essential basic sciences for medine. It is the study of Biological characteristics of microorganisms and their relationships with human hosts  Medical Bacteriology  Medical Viriology  Medical Mycology  Parasitology  Immunology

36. Purpose for learning of Medical Microbiology  Medical Microbiology Textbook http://basic.shsmu.edu.cn/passw/micro2/index.asp