1. MB304 Industrial & Environmental Biotechnology Module 1 Industrial Microbiology 1 Prepared by: Ms. Lim Yin Sze

2. Chapter 1 Introduction to Industrial Microbiology History of Industrial Microbiology Properties of a Useful Industrial Microorganism Major Products of Industrial Microorganism 2

3. Industrial Microbiology Industrial Microbiology refers to bulk production of any organic compound derived from microorganisms. 3

4. History of Industrial Microbiology Industrial microbiology originated with alcoholic fermentation processes, e.g. beer, wine. Subsequently, microbial processes were developed for the production of pharmaceuticals, food additive, enzymes and chemicals. Currently, methods for gene manipulation have given rise to new microbial products, most of it which are not naturally produced by the microb, e.g. human insulin. 4

5. StagesProducts of Fermentation Pre -1900Alcohol (yeast) Vinegar 1900 - 1940Baker’s yeast Glycerol, citric acid, lactic acid, and acetone/butanol 1940 - todayPharmaceutical products e.g. penicillin, streptomycin 1960 – todaySingle cell protein (SCP) 1979 - todayGenetically engineered products e.g. insulin History of Industrial Microbiology 5