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Published byLouisa Parker Modified over 9 years ago
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ExpressDetect® Mitch Sanders, CEO
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June 2009 ECI Biotech ECI Biotech is a premier developer of ExpressDetect® Diagnostics. ExpressDetect ® Diagnostics are simple, inexpensive, rapid, and safe. ECI has development agreements with industry leaders in Consumer and Professional Health Care. ECI Biotech has secured an aggregate of $18M in development funding, grants, and private equity.
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June 2009 Funding History Equity Financing$7.5 M Collaborative Seed and Growth Partners, LLC Vik Brothers International The GS Fuller Foundation Corporate Development Funding$5.0 M GrantsPhase I and II SBIR$1.9 M
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June 2009 Corporate Development Funding Current $1M SBIR Grants ProjectAwarded Yeast Diagnostic$200,870 PoC Wound Diagnostic, Phase I$208,311 Therapeutic Agent for Periodontal Disease, years 1+2$242,072 PoC Wound Diagnostic, Phase II$949,000 ProjectPending Detecting Trauma Induced Wound Infections $689,000 Yeast Diagnostic Phase II$1,000,000 Theranostic Grant $269,000
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June 2009 A series of high impact, low-cost, fast turnaround assays ExpressDetect ® Technology Summary Wound Care Oral Care Women’s Care UTI
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June 2009 Primary Markets $2.9 B Wound Care Market 9.2% (CAGR) 1. PoC for Clinics & Hospitals 2. Dressing sensor (Home health, VA, and nursing homes) 3. Consumer Band aids 4. Military Product for Combat Casualty Care $2.9 B Oral Care Market (Cleaners/Whiteners/Dentures) 4.9% (CAGR) 1. Consumer Strep Diagnostic 2. Consumer and Professional Gingivitis 3. Consumer and Professional Periodontitis Partner
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June 2009 Secondary Markets $1 B Women’s Health 16.6% (CAGR) 1. Yeast Diagnostic 2. BV-Tric-Yeast Consumer and Professional Care $3 B UTI Diagnostic 40% (CAGR) 1. Consumer UTI 2. Foley Catheter Market Partner
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June 2009 reporter molecules anchor peptide substrate Diagnostic Assay Formats Peptide covalently attached to microbead anchor and reporter molecule PRESENT ABSENT PATCH PoC
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June 2009 ExpressDetect ® Assay Technology InteractionSeparationDetection dual affinity tag peptide bead minutes
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June 2009 Advanced Wound Care is a $2.8 B Industry 14M Chronic Wounds Treated Annually Each patient is checked 8-10 x for infection Market Opportunity ($840M) Additional Market (50M Acute Wounds) Biopsy Visual exam only Swab 35% 53% 12%
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June 2009 Wounds need to be tested for bacterial load before treatment Visual Assessment Methods Inaccurate Current methods take 2-3 days to get results
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June 2009 Our test takes 10 minutes Low cost $16 (vs. $75 swab or $225 biopsy), simple, and safe Next steps, pre IDE meeting, clinical studies, and launch
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June 2009 Time Course of Color Reaction Dressing Sensor Time Course with A. baumannii. In the presence of culture media (BHI) or BHI + A. baumannii incubated for 0, 20, 40, or 60 minutes. Blue color indicates the presence of the pathogen. Scale Bar = 4 cm.
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June 2009 Inexpensive (COGS<3 cents), and safe enough for band-aids Sensor turns blue when infection is likely
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June 2009 Detection of Common Wound Pathogens Threshold is > 10 6 CFU/mL
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June 2009 Strong IP with 18 patent families issuing world-wide Additional design patents in preparation (See IP doc)
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June 2009 Clear regulatory path with FDA Time for Pre-IDE meetings
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June 2009 ExpressDetect ® Antibody Visual Signs Culture Real Time X Specificity X Low Cost $16$16+ $75-$225 Broad Spectrum X Active Detection X ?
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June 2009 Chronic Wound Opportunity for ECI = $840 Million 14M wounds; 4 tests/wound; $15/test 2008 2009 2010 2011 2012 Revenue (000)793 515 2,453 12,691 23,859 EBITDA (1,049) (2,056) (1,412) 4,474 12,339 Pretax/Net Income (1,223) (2,693) (1,706) 4,015 9,146
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June 2009 $3M $2M $3M $2M Manufacturing
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June 2009 ECI Organization Chart
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June 2009 ExpressDetect ® - simple, inexpensive, rapid, & safe Large Markets ($BB) Primary Products in Wound Care Pipeline (oral care, women’s health, & UTI) Significant revenue >$50M and liquidity opportunity
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