1. Diffusion MRI in Traumatic Brain Injury: Software Tools & Reference Material Workshop on Diffusion MRI in Traumatic Brain Injury: Software Tools and International Shared Data Repository Heidelberg, Germany, June 26 2013 National Institute of Neurological Diseases and Stroke, National Institutes of Health

3. DTI Protocol Number of diffusion gradient directions = 41 Number of b = 0 images: 5 b value = 1000 TR/TE = 8773 ms/52 ms Flip angle = 90 o FOV = 250 x 250 x 146 mm 3 Matrix size = 96 x 96 Slice number = 56 Slice gap = 0 Resolution = 2.6 x 2.6 x 2.6 mm 3 Sense factor = 2 Total scan time = 7 min High resolution 3D T1 weighted anatomical image FOV = 256 x 256 x 146 mm 3 Resolution = 1 x 1 x 1 mm 3 TR/TE = 10 ms/4.6 ms Flip angle = 8 o Total scan time = 5 min

4. 1.Application fields 2.Artifacts and data acquisition techniques 3.Quality control and preprocessing 4.Processing and visualization 5.Quantitative analysis 6.Multimodal studies 7.Results interpretation 1-14

5. Anterior corona radiata L Genu of corpus callosum Anterior limb of internal capsule L External capsule L Posterior limb of internal capsule L Retrolenticular part of internal capsule L Superior longitudinal fasciculus L Posterior thalamic radiation (include optic radiation) L Splenium of corpus callosum Cingulum (cingulate gyrus) L

6. indexlabelFA Value 1Middle cerebellar peduncle0.348497 2Pontine crossing tract (a part of MCP)0.414859 3Genu of corpus callosum0.404761 4Body of corpus callosum0.325766 5Splenium of corpus callosum0.52199 6Fornix (column and body of fornix)0.373117 7Corticospinal tract R0.489382 8Corticospinal tract L0.467688 9Medial lemniscus R0.534683 10Medial lemniscus L0.544942 11Inferior cerebellar peduncle R0.277768 12Inferior cerebellar peduncle L0.289317 13Superior cerebellar peduncle R0.33122 14Superior cerebellar peduncle L0.351684 15Cerebral peduncle R0.468039 16Cerebral peduncle L0.455127 17Anterior limb of internal capsule R0.440927 18Anterior limb of internal capsule L0.40953 19Posterior limb of internal capsule R0.477165 20Posterior limb of internal capsule L0.487003 21Retrolenticular part of internal capsule R0.492149 22Retrolenticular part of internal capsule L0.502794 23Anterior corona radiata R0.336596 24Anterior corona radiata L0.377241 25Superior corona radiata R0.44589 26Superior corona radiata L0.399122 27Posterior corona radiata R0.393846 28Posterior corona radiata L0.385009 29 Posterior thalamic radiation (include optic radiation) R 0.462773 30 Posterior thalamic radiation (include optic radiation) L 0.492928 IndexLabelFA Value 31 Sagittal stratum (include inferior longitidinal fasciculus and inferior fronto-occipital fasciculus) R 0.447041 32 Sagittal stratum (include inferior longitidinal fasciculus and inferior fronto-occipital fasciculus) L 0.440027 33External capsule R0.322001 34External capsule L0.333932 35Cingulum (cingulate gyrus) R0.177297 36Cingulum (cingulate gyrus) L0.154754 37Cingulum (hippocampus) R0.227064 38Cingulum (hippocampus) L0.226276 39 Fornix (cres) / Stria terminalis (can not be resolved with current resolution) R 0.45711 40 Fornix (cres) / Stria terminalis (can not be resolved with current resolution) L 0.432283 41Superior longitudinal fasciculus R0.346349 42Superior longitudinal fasciculus L0.346567 43 Superior fronto-occipital fasciculus (could be a part of anterior internal capsule) R 0.333865 44 Superior fronto-occipital fasciculus (could be a part of anterior internal capsule) L 0.300206 45Uncinate fasciculus R0.433751 46Uncinate fasciculus L0.461698 47Tapetum R0.588981 48Tapetum L0.610701 Automated FA measurements

9. The American College of Radiology (ACR) continues to support innovation along a variety of fronts. Recently, the ACR, in partnership with Siemens Corporate Research and Technology (SCR), has been working with the DOD’s Telemedicine and Advanced Technology Research Center on a project to explore unique solutions to diagnose Traumatic Brain Injury (TBI).

10. Globus Online and CI Computation Institute – Multi-discipline research institute – Aims to advance science through innovative computational approaches Globus Online – Hosted Software-as-a-Service for researchers – Provides high performance data transfer, user and credential management, group management. – Web, REST service, and CLI

12. Diffusion MRI in Traumatic Brain Injury: Software Tools & Reference Material Workshop on Diffusion MRI in Traumatic Brain Injury: Software Tools and International Shared Data Repository Heidelberg, Germany, June 26 2013