1. ONCOLOGY Dr. Walid Daoud Assistant Professor

2. Oncology Oncology is the study of tumors (neoplasms) - Benign neoplasm:. Growth of the same cells as the tissue.. Growth of the same cells as the tissue.. It is contained in a capsule.. It is contained in a capsule.. It does not invade the surrounding tissue.. It does not invade the surrounding tissue.. It place pressure on the surrounding and. It place pressure on the surrounding and once removed it does not regrow. once removed it does not regrow.

3. Oncology - Malignant neoplasm:. Growth not resemble the same cells as tissue.. Growth not resemble the same cells as tissue.. It is not capsulated and able to spread to normal tissue.. It is not capsulated and able to spread to normal tissue.. Invasive growth by direct invasion or. Invasive growth by direct invasion or metastasis metastasis

4. Nomenclature of Tumors Nomenclature depends upon the tissue from which the tumor originates (histogenesis). 4 tissue types: - Epithelial tissue: skin and internal lining. - Connective tissue: cartilage, bone, muscle - Hematopoietic tissue: white and red cells - Nervous tissue: nerve, glial cells, meninges

5. Benign Tumors of Epithelial and Connective Tissue Origin To indicate a benign tumor add the suffix -oma Benign Tumor of Medical Term skin tissue gland tissue blood vessel bone striated muscle papillomaadenomahemangiomaosteomarhabdomyoma

6. Malignant Tumors of Epithelial Tissue Origin To indicate a malignant tumor of epithelial origin add the suffix –carcinoma to the word root or the word carcinoma with the affected structure Malignant Tumor of Medical Term glandpancreas skin tissue stomach glandular epithelium lung glandular tissue adenocarcinoma pancreatic carcinoma papillocarcinoma gastric adenocarcinoma adenocarcinoma of the lung

7. Malignant Tumors of Connective Tissue Origin To indicate a malignant tumor of connective tissue origin add the suffix –sarcoma to the word root or the word sarcoma with the affected structure Malignant Tumor of Medical Term fibrous tissue blood vessel cartilage synovial tissue smooth muscle fibrosarcomahemangiosarcomachondrosarcoma synovial sarcoma leiomyosarcoma

8. Hematopoietic Tissue Leukemias Malignant neoplasms of hemopoietic cells. Examples of leukemia: Cellular involvement Medical term Lymphocytes Bone marrow Plasma cell Acute/chronic lymphocytic Acute/chronic myelogenous Plasma cell leukemia

9. Hematopoietic Tissue Lymphomas Malignant neoplasms of lymphatic system. Examples of lymphomas: Cellular involvement Medical term Lymph nodes Plasma cell, bone marrow Malignant granuloma - lymphosarcoma. - Hodgkin disease. Multiple myeloma

10. Histogenesis of neoplasms Neoplastic classification based upon histogenesis: benign and malignant. See page: 332-333

11. Staging of Cancer Staging is used to define the extent of cancer TNM classification: T Primary tumor N Regional lymph nodes M Distant metastasis See page: 335

12. Grading of malignant tumor Grading is histologic evaluation of neoplasm Grade 1: cells closely resemble the tissue they arise from. they arise from. Grade 4: Cells do not resemble the tissue they arise from (anaplasia) and this carries poor prognosis. they arise from (anaplasia) and this carries poor prognosis. Grade 2 and 3: intermediate grades.

13. WR/CF related to Oncology ExampleMeaningWR/CF neur/o/bast/oma carcin/o/gen dys/kerat/osis leiomy/oma embryoniccancerhorny smooth muscle blast/ocarcin/okerat/oleiomy/o

14. WR/CF related to Oncology ExampleMeaningWR/CF medull/ary ne/oplasm onc/o/logy papill/oma rhabdomy/oma marrownewtumor nipple or epithelial skeletal muscle medull/one/oonc/opapill/orhabdomy/o

15. Suffixes related to Oncology ExampleMeaningSuffix erythr/o/plakia dys/plasia chem/o/therapy plate formation or molding treatment-o/plakia-o/plasia-o/therapy

16. Surgical Terms Related to Oncology Page 337-338

17. Answer Worksheets 1-4 Page 340-344