1. HERPES GENITALIS & SYPHILIS
Mia Smoljan
Mentor: A. Žmegač Horvat

2. Herpes genitalis STD caused by HSV Remissions and relapses Symptoms:
reddening of the skin with small, fluid-filled blisters and ulcers
initial episodes may be more severe – inguinal lymphadenopathy, fever, malaise, headache
Diagnosis:
PCR
Tzank test
Treatment: Acyclovir

4. Herpes neonatalis
Dangerous complication that affects babies born while mother has an active infection during parturition
Symptoms appear between 1st and 2nd week of life
Can affect:
skin
CNS
eye
mouth
liver
lungs
Prevention: Cesarean section
Treatment: Acyclovir

5. Syphilis Chronic STI caused by Treponema pallidum
Acquired via direct sexual contact with the infectious lesions of a person with syphilis
PRIMARY SYPHILIS: a few weeks after infection
chancre/hard ulcer
after 4 to 6 weeks heals spontaneously

7. SECONDARY SYPHILIS:
1–6 months (commonly 6 to 8 weeks) after the primary infection
symmetrical reddish-pink non-itchy rash on the trunk and extremities
condylomata lata (rash becomes flat, broad, whitish lesions)
most contagious stage!!
meningismus, enlarged lymph nodes, fever....

9. TERTIARY SYPHILIS: 1–10 years after the initial infection
formation of gummas =
soft, tumor-like balls of inflammation – granulomas
neuropathic joint disease
neurosyphilis
tabes dorsalis
cardiovascular syphilis – ascending aorta!!
cor bovinum

10. Diagnosis: serology (VDRL antibody test, TPHA)
Treatment:
penicillin