1. I.The Historical Development of Microbiology A.The Discovery and Significance of Microorganisms B.Vaccines and Antimicrobial Therapy C.Microbes and Industry D.Emergent Diseases and the Post-Antibiotic Era

2. I. A.Discovery and Significance Discovery of microorganisms –1670svan Leeuwenhoek

3. I. A.Discovery and Significance Spontaneous Generation vs Biogenesis –1688 Redi –1750 Needham vs Spallanzani –1860s - 70s Pasteur & Tyndall

4. I. A.Discovery and Significance Microbes and Disease –1790 Jenner –1835 Bassi –1847 Semmelweis –1849 Snow –1867 Lister –1860s - 80s Pasteur –1870s - 80s Koch

5. I. A.Discovery and Significance Pure Culture Technique –1870s - 80s Koch –Streak Plate Method

8. I. A.Discovery and Significance Microbes and the Environment –late 1800s Winogradsky Beijerinck

9. I. B.Vaccines and Antimicrobial Therapy Vaccines –1790sJenner –1860s-70sPasteur –20th century accomplishments

10. I. B.Vaccines and Antimicrobial Therapy Antimicrobial Therapy –Pre-antibiotic era –Antibiotics

11. I. C.Microbes and Industry Water and Wastewater Treatment Food Microbiology Recombinant DNA Technology

12. I. D.Emergent Diseases and the Post-Antibiotic Era “New” Diseases Resurgence of “old” diseases Microbial resistance to drugs Immunosupression Are we in a “post-antibiotic” era?