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This article and any supplementary material should be cited as follows: Foecking EM, Fargo KN, Coughlin LM, Kim JT, Marzo SJ, Jones KJ. Single session.

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Presentation on theme: "This article and any supplementary material should be cited as follows: Foecking EM, Fargo KN, Coughlin LM, Kim JT, Marzo SJ, Jones KJ. Single session."— Presentation transcript:

1 This article and any supplementary material should be cited as follows: Foecking EM, Fargo KN, Coughlin LM, Kim JT, Marzo SJ, Jones KJ. Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve. J Rehabil Res Dev. 2012;49(3):451–58. http://dx.doi.org/10.1682/JRRD.2011.03.0033 Slideshow Project DOI:10.1682/JRRD.2011.03.0033JSP Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve Eileen M. Foecking, PhD; Keith N. Fargo, PhD; Lisa M. Coughlin, MD; James T. Kim, MD; Sam J. Marzo, MD; Kathryn J. Jones, PhD

2 This article and any supplementary material should be cited as follows: Foecking EM, Fargo KN, Coughlin LM, Kim JT, Marzo SJ, Jones KJ. Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve. J Rehabil Res Dev. 2012;49(3):451–58. http://dx.doi.org/10.1682/JRRD.2011.03.0033 Slideshow Project DOI:10.1682/JRRD.2011.03.0033JSP Aim – Test whether electrical stimulation (ES) adminis- tered immediately after crush injury further decreases time for complete recovery from facial paralysis. Relevance – Peripheral nerve injuries lead to various conditions, including paresis or paralysis. – Daily ES to facial nerve proximal to injury affects early events in nerve regeneration process in rats by initiating axon sprout formation.

3 This article and any supplementary material should be cited as follows: Foecking EM, Fargo KN, Coughlin LM, Kim JT, Marzo SJ, Jones KJ. Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve. J Rehabil Res Dev. 2012;49(3):451–58. http://dx.doi.org/10.1682/JRRD.2011.03.0033 Slideshow Project DOI:10.1682/JRRD.2011.03.0033JSP Methods Rats received unilateral facial nerve crush injury. – Electrode positioned on nerve proximal to injury. Rats received 30 min of ES daily for: – 1 d (day of injury), 2 d, 4 d, 7 d, or daily until complete functional recovery. – Untreated animals received no ES. Rats were observed daily for return of facial function.

4 This article and any supplementary material should be cited as follows: Foecking EM, Fargo KN, Coughlin LM, Kim JT, Marzo SJ, Jones KJ. Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve. J Rehabil Res Dev. 2012;49(3):451–58. http://dx.doi.org/10.1682/JRRD.2011.03.0033 Slideshow Project DOI:10.1682/JRRD.2011.03.0033JSP Results One session of ES was as effective as daily stimulation at enhancing recovery of most functional parameters.

5 This article and any supplementary material should be cited as follows: Foecking EM, Fargo KN, Coughlin LM, Kim JT, Marzo SJ, Jones KJ. Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve. J Rehabil Res Dev. 2012;49(3):451–58. http://dx.doi.org/10.1682/JRRD.2011.03.0033 Slideshow Project DOI:10.1682/JRRD.2011.03.0033JSP Conclusions Use of one 30 min session of ES should be studied as possible treatment strategy for human patients with paralysis as result of acute nerve injuries.

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