1. www. Clinical trial results.org  Major Endpoints: Death, MI, stent thrombosis, TLR, TVR, MACE, and CKMB >3x nl  Major Endpoints: Death, MI, stent thrombosis, TLR, TVR, MACE, and CKMB >3x nl PTCA of sidebranch with final kiss n=206 n=206 Cypher of side branch with final kiss (“crush”, “culotte”, “Y”, or other technique) n=207 Cypher of side branch with final kiss (“crush”, “culotte”, “Y”, or other technique) n=207 413 patients at 28 centers in 5 countries with true bifurcation lesions received Cypher stents in the main vessel Randomized. Clinical follow-up at 6 months 413 patients at 28 centers in 5 countries with true bifurcation lesions received Cypher stents in the main vessel Randomized. Clinical follow-up at 6 months The Randomized Nordic Bifurcation Trial Steigen TC et al. ACC 2006

2. www. Clinical trial results.org Nordic Bifurcation Trial: Methods and Results PTCACypher (“crush”, “culotte”, “Y”, or other technique) n=206n=207 MV stented (%) 10098.5NS SB stented (%) 4.395.1<0.001 Kissing balloon (%) 3274<0.001 Tx successful (%) 9795NS Presented at TCT 2006 Steigen TC et al. ACC 2006

3. www. Clinical trial results.org Nordic Bifurcation Study Major Endpoints Primary Endpoint Presented at TCT 2006 In-hospital MI (%) p=0.30 CKMB >3x nl 6 month MACE (%) p=0.01 Steigen TC et al. ACC 2006