1. Supplementary Figure 1A
Residue 22
D (Asp)
E (Glu)
Residue 81
I (Ile)
V (Val)
Residue 132
H (His)
Y (Try)
Residue 154
Residue 160
A (Ala)

2. Residue 270N Residue 270I Residue 301S Residue 301T
T (Thr)
N (Asp)
I (Ile)
Residue 270I
Residue 301T
L (Leu)
Residue 301S
S (Ser)
Residue 302
G(Gly)
Residue 380,383,386
K (Lys)
R(Arg)

3. Supplementary Figure 1B
Residue 68
I (Ile)
V (Val)
Residue 169
A (Ala)
R (Arg)
K (Lys)
Residue 231
Residue 303
T (Thr)
Residue 391
Supplementary Figure 1B

4. Supplementary Figure 1C
Residue 140
I (Ile)
T (Thr)
Supplementary Figure 1C