1. Copyright ©2009 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved. The Pharmacy Technician: Foundations and Practices Mike Johnston, Karen Davis, and Jeff Gricar The Pharmacy Technician FOUNDATIONS AND PRACTICES Chapter 11 Introduction to Sterile Products

2. Copyright ©2009 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved. The Pharmacy Technician: Foundations and Practices Mike Johnston, Karen Davis, and Jeff Gricar Figure 11.1 A technician dressed in sterile clothing.

3. Copyright ©2009 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved. The Pharmacy Technician: Foundations and Practices Mike Johnston, Karen Davis, and Jeff Gricar Basic Equipment Used in Sterile Compounding Laminar flow hood—device containing a HEPA filter; used for preparing sterile products Vertical flow hood—a laminar flow hood that blows air from the top to the workspace; not recommended for chemotherapy products

4. Copyright ©2009 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved. The Pharmacy Technician: Foundations and Practices Mike Johnston, Karen Davis, and Jeff Gricar Basic Equipment Used in Sterile Compounding (cont.) Biological safety cabinet—a vertical laminar flow hood recommended to provide protection for the worker, the work environment, and the drug

5. Copyright ©2009 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved. The Pharmacy Technician: Foundations and Practices Mike Johnston, Karen Davis, and Jeff Gricar Figure 11.2 A laminar flow hood.

6. Copyright ©2009 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved. The Pharmacy Technician: Foundations and Practices Mike Johnston, Karen Davis, and Jeff Gricar Figure 11.3 An example of a biological safety cabinet.

7. Copyright ©2009 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved. The Pharmacy Technician: Foundations and Practices Mike Johnston, Karen Davis, and Jeff Gricar Basic Supplies Used in Sterile Compounding Needles—consists of two parts: the shaft and the hub Syringes—parts of a syringe are the barrel and the plunger IV bags—plastic bags used for diluting a solution and administering intravenous medications to patients

8. Copyright ©2009 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved. The Pharmacy Technician: Foundations and Practices Mike Johnston, Karen Davis, and Jeff Gricar Figure 11.4 The parts of a needle.

9. Copyright ©2009 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved. The Pharmacy Technician: Foundations and Practices Mike Johnston, Karen Davis, and Jeff Gricar Figure 11.5 The parts of a syringe.

10. Copyright ©2009 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved. The Pharmacy Technician: Foundations and Practices Mike Johnston, Karen Davis, and Jeff Gricar Figure 11.6 The parts of an IV.

11. Copyright ©2009 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved. The Pharmacy Technician: Foundations and Practices Mike Johnston, Karen Davis, and Jeff Gricar Administration of Sterile Products Injection is the most common route of administration for sterile products Most common injectable routes: –Intravenous—in the vein –Intramuscular—in the muscle –Subcutaneous—in the skin

12. Copyright ©2009 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved. The Pharmacy Technician: Foundations and Practices Mike Johnston, Karen Davis, and Jeff Gricar Administration of Sterile Products (cont.) Other injectable routes that are used less frequently: –Intradermal—in the dermis of the skin –Intrathecal—in the spine

13. Copyright ©2009 by Pearson Education, Inc. Upper Saddle River, New Jersey 07458 All rights reserved. The Pharmacy Technician: Foundations and Practices Mike Johnston, Karen Davis, and Jeff Gricar Chemotherapy and Cytotoxic Drugs Designed to damage the DNA of rapidly dividing cancer cells Lack specificity; any rapidly dividing cells in the body, whether normal or cancerous, become damaged Pharmacy staff who prepare and dispose of cytotoxic agents are personally at risk of irreparable DNA damage that could lead to birth defects