2. 7 Deadly Sins of PowerPoint 1.The speaker read the slides to us60.4% 2.Text so small I couldn't read it (Slide 8) 50.9% 3.The speaker used Full sentences instead of bullet points on each slide and it was too much information (PowerParagraph)47.8% 4.Slides hard to see because of color choice37.1% 5.Moving/flying text or graphics24.5% 6.Annoying use of sound 7.Overly complex diagrams or charts22.0% 47.8% 22.0% 60.4% 24.5% 22.0% 50.9 37.1%

3. 7. Overly Complex Diagrams GFR Proteinuria Aldosterone release Glomerular sclerosis Angiotensin II Plays a Central Role in Organ Damage Adapted from Willenheimer R et alEur Heart J1999; 20(14): 997  1008, Dahlöf BJ Hum Hypertens1995; 9(suppl 5): S37  S44, Daugherty A et alJ Clin Invest2000; 105(11): 1605  1612, Fyhrquist F et alJ Hum Hypertens1995; 9(suppl 5): S19  S24, Booz GW, Baker KMHeart Fail Rev1998; 3: 125  130, Beers MH, Berkow R, eds.The Merck Manual of Diagnosis and Therapy. 17th ed. Whitehouse Station, NJ: Merck Research Laboratories 1999: 1682  1704, Anderson SExp Nephrol1996; 4(suppl 1): 34  40, Fogo ABAm J Kidney Dis2000; 35(2):179  188 A II AT 1 receptor Atherosclerosis* Vasoconstriction Vascular hypertrophy Endothelial dysfunction LV hypertrophy Fibrosis Remodeling Apoptosis Stroke DEATH *preclinical data LV = left ventricular; MI = myocardial infarction; GFR = glomerular filtration rate Hypertension Heart failure MI Renal failure Adapted from Willenheimer R et alEur Heart J1999; 20(14): 997  1008, Dahlöf BJ Hum Hypertens1995; 9(suppl 5): S37  S44, Daugherty A et alJ Clin Invest2000; 105(11): 1605  1612, Fyhrquist F et alJ Hum Hypertens1995; 9(suppl 5): S19  S24, Booz GW, Baker KMHeart Fail Rev1998; 3: 125  130, Beers MH, Berkow R, eds.The Merck Manual of Diagnosis and Therapy. 17th ed. Whitehouse Station, NJ: Merck Research Laboratories 1999: 1682  1704, Anderson SExp Nephrol1996; 4(suppl 1): 34  40, Fogo ABAm J Kidney Dis2000; 35(2):179  188 *preclinical data LV = left ventricular; MI = myocardial infarction; GFR = glomerular filtration rate

4. The Role of Angiotensin II in Organ Damage GFR Proteinuria Aldosterone release Glomerular sclerosis AII AT receptor Atherosclerosis* Vasoconstriction Vascular hypertrophy Endothelial dysfunction LV hypertrophy Fibrosis Remodeling Apoptosis Stroke Hypertension Heart failure MI Renal failure *PRE CLINICAL DATA DEATH

5. 392. Angiotensin I Non- Tissue plasminogen activator (tPA) CAGE Inactive Hollenberg NK, Fisher ND, Price DA. Hypertension. 1998;32:387- Sodium and fluid retention Vasoconstriction Sympathetic activation Cell growth 1 - ACE: angiotensin-converting enzyme CAGE: chymase-angiotensin generating enzyme Angiotensinogen Angiotensin II ATreceptor ACE pathways - Cathepsin G Chymase Renin ACE ACE pathways Bradykinin fragments RAS and high BP

6. 6. Annoying Use of Sounds 1.Saved list of URLs –F–Favorites in IE –B–Bookmarks in Netscape 2.Create shortcuts on a browser toolbar –L–Links Toolbar in IE –P–Personal Toolbar in Netscape 3.Associate a URL with the Home button

7. 5. Moving/flying Text or Graphics 1.The speaker read the slides to us60.4% 2.Text so small I couldn't read it (Slide 8) 50.9% 3.The speaker used Full sentences instead of bullet points on each slide and it was too much information at once47.8% 4.Slides hard to see because of color choice37.1% 5.Moving/flying text or graphics24.5% 6.Annoying use of sounds22.0% 7.Overly complex diagrams or charts22.0% 47.8%22.0% 60.4% 24.5% 22.0% 50.9 37.1%

8. 7 Deadly Sins of PowerPoint 1.The speaker read the slides to us60.4% 2.Text so small I couldn't read it (Slide 8) 50.9% 3.The speaker used Full sentences instead of bullet points on each slide and it was too much information. (PowerParagraph)47.8% 4.Slides hard to see because of color choice37.1% 5.Moving/flying text or graphics24.5% 6.Annoying use of sounds 7.Overly complex diagrams or charts22.0% 47.8% 22.0% 60.4% 24.5% 22.0% 50.9 37.1%

9. 4. Hard To Read – Bad Color Choice Type a URL in the address bar and press enter Click on hyperlinks – text or graphics Click the Back button Click the Forward button Click the Home button

10. 3. Power Paragraph Too many experts look at PowerPoint from the technical perspective – what features do people use and how to use the features. A recent survey took a different perspective. For the first time, the audience perspective on PowerPoint presentations was considered. In September of 2003, 159 people were asked what they found most annoying about the PowerPoint presentations that they see. The results of this survey have important insights for presenters at all levels.

11. OutcomeNo.Events, Active DrugofTreatment /RR (95% CI) RegimentDose Trials ControlRR (95% CI)0.40.7 1.0 Stroke DiureticsHigh988 / 2320.49 (0.39-0.62) DiureticsLow4191 / 3470.66 (0.55-0.78)  -Blockers4147 / 3350.71 (0.59-0.86) HDFPHigh1102 / 1580.64 (0.50-0.82) Coronary Heart Disease DiureticsHigh 11211 / 3310.99 (0.83-1.18) DiureticsLow4215 / 3630.72 (0.61-0.85)  -Blockers4243 / 4590.93 (0.80-1.09) HDFPHigh1171 / 1890.90 (0.73-1.10) Congestive Heart Failure DiureticsHigh9 6 / 350.17 (0.07-0.41) DiureticsLow3 81 / 1340.58 (0.44-0.76)  -Blockers2 41 / 1750.58 (0.40-0.84) Total Mortality DiureticsHigh 11224 / 3820.88 (0.75-1.03) DiureticsLow4514 / 7130.90 (0.81-0.99)  -Blockers4383 / 7000.95 (0.84-1.07) HDFPHigh1349 / 4190.83 (0.72-0.95) Cardiovascular Mortality DiureticsHigh 11124 / 2300.78 (0.62-0.97) DiureticsLow4237 / 3900.76 (0.65-0.89)  -Blockers4214 / 4100.89 (0.76-1.05) HDFPHigh1195 / 2400.81 (0.67-0.97) Psaty BM, Smith NL, Siscovick DS, et al Health outcomes associated with antihypertensive therapies used as first-line agents. JAMA 1997; 277: 739-745 Treatment Better Worse Meta-Analysis of Randomized, Placebo-Controlled Clinical Trials in Hypertension According to First-Line Treatment Strategy 2. Text Too Small

12. 2. Text too Small Information Resources Online versions of newspapers, magazines, government documents, research reports, databases and books. Communication Personal and business use of newsgroups, online chat, e-mail, and voice over IP. Entertainment Online reviews of restaurants, movies, theater, musical events, and books. You can download music, play interactive games with people around the world, watch film clips using the Internet. Retail Business New ways of doing business by providing product information, advertising, and online sales and services online. Business Communications Many business firms that have multiple locations throughout the world transmit data over the Internet through Virtual Private Networks. Software Downloads Hundreds of thousands of programs are available to you on the Internet. These programs, many of which you can download free or for a small fee, include utilities, word processors, various kinds of graphics programs, and games.

13. How is the Internet used? Information Resources Online versions of newspapers, magazines, government documents, research reports, databases and books. Communication Personal and business use of newsgroups, online chat, e-mail, and voice over IP. Entertainment Online reviews of restaurants, movies, theater, musical events, and books. You can download music, play interactive games with people around the world, watch film clips using the Internet. Retail Business New ways of doing business by providing product information, advertising, and online sales and services online. Business Communications Many business firms that have multiple locations throughout the world transmit data over the Internet through Virtual Private Networks. Software Downloads Hundreds of thousands of programs are available to you on the Internet. These programs, many of which you can download free or for a small fee, include utilities, word processors, various kinds of graphics programs, and games.

14. 2. Text too Small Information Resources Online versions of newspapers, magazines, government documents, research reports, databases and books. Communication Personal and business use of newsgroups, online chat, e-mail, and voice over IP. Entertainment Online reviews of restaurants, movies, theater, musical events, and books. You can download music, play interactive games with people around the world, watch film clips using the Internet. Retail Business New ways of doing business by providing product information, advertising, and online sales and services online. Business Communications Many business firms that have multiple locations throughout the world transmit data over the Internet through Virtual Private Networks. Software Downloads Hundreds of thousands of programs are available to you on the Internet. These programs, many of which you can download free or for a small fee, include utilities, word processors, various kinds of graphics programs, and games.

15. 1. Speaker read slide to us