1. Designing A Portable Neonatal Intensive Care Unit (BabyPod) For Emergency Situations BME 401: Preliminary Design Presentation Kasidis Horsangchai, Doreen Sheen, and David Yang Frank Yin, M.D., Ph.D. Laura Marquardt Group 23: Mentor: Teaching Assistant:

2. Client Karen M. Wickline, M.D. St. Louis Children’s Hospital Neonatal Intensive Care Unit (NICU) Washington University Associate Professor of Pediatrics

3. Pre-Term Birth 1 in 10 babies are born premature. (15 million/year)

4. Pre-Term Birth 1 million babies die each year due to pre-term complications.

5. Thermal Instability Three Main Disadvantages: 1. Poor thermal insulation 2. Large surface area to volume ratio 3. Small mass to act as heat sink

6. NICU Isolettes  Stable Thermal Environment, 36.5 ± 0.5˚C  Humidity Control  Clear Walls and Hood  Easy Access Doors GE Giraffe Omnibed

7. Problem Definition  Natural Disaster  At-Home Birth  Transportation between Hospitals 1. Thermal Regulation of Pre-Term Babies 2. In Emergency Situations

8. Prior Designs Neonatal Transport Incubator Embrace Infant Warmer

9. BabyPod Our product, BabyPod, is an emergency alternative neonatal intensive care unit that is low-cost and portable. BabyPod will significantly decrease the risk of over-heating and under-heating by introducing a temperature regulation system driven by a closed- feedback loop.

10. Specifications ACTUATOR Temperature – 0.1 degrees Celsius sensitivity. Be able to regulate baby’s temperature between 36-37 degrees Celsius Humidity – have a container for water, be able to actively control humidity (user input) MONITOR LCD Display Low Energy Demand POWER SOURCE Stand Alone Rechargeable Small Size Reliable/ Stable Last At Least One Day Desired Specifications: CONTAINER Insulated Compatible with other devices Padded interior SENSORS Breathing Monitor POWER SOURCE Compatible with other power sources (Able to draw energy from these sources) Necessary Specifications: CONTAINER Length > 50cm Width > 30cm Height (of baby compartment) > 20cm Face of baby visible Weight – easily carried by one person (< 10 kgs) Be able to support the weight of 2kgs Allows O2 (airflow) Secured baby Durable MECHANICAL Stable Interior Reduce Jarring Heat Resistant/Durable Material Light Weight Material 20N force test SENSORS Low Power Demand Small Skin Touch Minimal Wiring Interface with a display Software ADC, DAC, DSP (low cost, reliable) Humidity controller Temperature

11. Specifications  Rechargeable, stand-alone power source lasting minimum of 24 hours  Well-Insulated  Regulate temperature with a 0.1 ºC sensitivity  System to actively control humidity  Easily carried by one person (<10 kgs)  Secured Baby  Mechanism to reduce jarring  Face of baby visible  Easily opened and closed

12. Delegations Phase 1Phase 2Phase 3 Kasidis Horsangchai  Temperature Regulation/Actuators X X  Circuit Design X X X  Workflow for Software X Doreen Sheen  Literature Search X  Material Research X  Budget X X  CAD X X David Yang  Sensors X X  Power Source X X  Mechanical Design X X  Website X X

13. Deadlines and Milestones 9/2410/110/810/1510/2210/2911/511/1211/1911/2612/3 Preliminary Report Web Page DesignSafe Circuit Designs Mechanical Designs CAD Drawings Progress Report Final Circuit Design Final Mechanical Design Final CAD Drawings Final Report Due Date In Progress Phase 1 Phase 2Phase 3

14. Questions?

15. References  Faculty bio: Karen M. Wickline, M.D. Washington University Department of Pediatrics..  March of Dimes, PMNCH, Save the Children, WHO. Born Too Soon: The Global Action Report on Preterm Birth. Eds CP Howson, MV Kinney, JE Lawn. World Health Organization. Geneva, 2012.  GE Healthcare. The Giraffe Family: Helping Make Sick Babies Well.. 2010.  Ngo, Denise. “Fetching Incubator Backpack May Save Newborn Lives.” PopSci.. May 19, 2010.  “The Embrace Infant Warmer is a Product with a Mission.” Embrace..