1. BY JASON LESE Cardiomyopathy

2. What is Cardiomyopathy? (CMP) Deterioration of heart muscle Becomes enlarged, thick or rigid  Scar tissue Pumping blood becomes more difficult, electrical rhythm can get off beat. CMP can lead to heart failure, arrhythmias, and heart valve problems

3. Where does it come from?! :P CMP can be inherited  Parents give it to you via a gene.  Mistakes/errors in genes may result in CMP. Can also be acquired  Other diseases and conditions can cause CMP  Examples:  High blood pressure  Heart tissue problem from previous heart attack  Pregnancy  Nutritional deficiencies.  Abuse of cocaine or anti-depressants  Excessive use of alcohol However, most of the time the cause of CMP is unknown.

4. Types: Dilated Cardiomyopathy Dilated CMP can be caused by a few medical problems Most common form Common age range: 20-60 Affects atria and ventricles Starts in left ventricle, stretches it out and thins Heart cannot pump, will result in heart failure Can also result in heart valve problems, blood clots and arrhythmias.

5. Types: Hypertrophic CMP Hypertrophic CMP is passed down genetically 1:500, men and women equally Common cause for cardiac arrest in young people Walls of ventricles (left) thicken; difficult to fill with blood. Different things can happen from here:  Blocks blood flow  Harm mitral valve: backflow  Nonobstructive Hypertrophic

6. Restrictive CMP Restrictive CMP is caused by amyliodosis Found in older adults Atria enlarged because ventricles cannot fill up Walls stiff, not thick Blood flow reduced Causes arrhythmias and heart failure

7. What is it? Jose Cuervo Especial Comes from long term abuse of alcohol Toxic effects of alcohol on heart muscle  Cannot pump Leads to heart failure Alcohol Cardiomyopathy

8. Signs and Symptoms Some people never experience the symptoms Symptoms of heart failure:  Shortness of breath  Fatigue  Swelling in ankles, feet, legs or abdomen.  Swelling in veins of the neck Other symptoms related to CMP:  Dizziness  Lightheadedness  Fainting during physical activity  Chest pain  Arrhythmias  Heart murmur

9. Medication (for dilated CMP) Other treatments ACE inhibitors Diuretics Beta blockers Iatrogenic/implanted pacemakers Coronary artery bypass Stem cells  Does it work? Heart transplants  Last resort Lifestyle changes Treatment

10. Treatment: Ventricular Assist Device Can be used short-term or long-term. Assist right or left ventricle  Sometimes both Pumps blood out of ventricle, into aorta Cable controls unit; sticks out of abdomen

11. Treatment: Defibrillators Ventricular fibrillation  Rapid, erratic heart beats Electrical device:  Shocks heart to a stop Heart rhythmically corrects

12. Homework: Broken Heart Syndrome Takotsubo Cardiomyopathy Weakening of heart muscle caused by emotional stress Can you die of a broken heart?

13. Bibliography "What Is Cardiomyopathy?" - NHLBI, NIH. N.p., n.d. Web. 28 Feb. 2013. "Cardiomyopathy." Wikipedia. Wikimedia Foundation, 28 Feb. 2013. Web. 28 Feb. 2013. "What Is Cardiomyopathy?" What Is Cardiomyopathy. N.p., n.d. Web. 28 Feb. 2013. "Takotsubo Cardiomyopathy." Wikipedia. Wikimedia Foundation, 20 Feb. 2013. Web. 28 Feb. 2013. Staff, Mayo Clinic. "Definition." Mayo Clinic. Mayo Foundation for Medical Education and Research, 02 Mar. 2012. Web. 28 Feb. 2013. "Dilated Cardiomyopathy: MedlinePlus Medical Encyclopedia." U.S National Library of Medicine. U.S. National Library of Medicine, n.d. Web. 28 Feb. 2013. CNN. Cable News Network, n.d. Web. 01 Mar. 2013.