1. School of Biomedical Engineering, Science & Health Systems WWW.BIOMED.DREXEL.EDU/ResearchPortfolio/ V 1.0 SD [020118] REHABILITATION ENGINEERING & MUSKULOSKELETAL BIOMECHANICS RESEARCH Children afflicted with muscular dystrophy loose function of their arms progressively. The objective of this project is to study the characteristics of the decline in muscle power and to develop a powered orthotic device that will enable them to continue to use their arms. Faculty: Rami Seliktar, Ph.D. Collaborating Researchers: Tariq Rahman, Ph.D., AI duPont Hospital for Children and Alberto Esquenazi, M.D., Moss Rehabilitation Hospital Graduate Students: Roscoe Bowen, Riccardo Conti, Dohyung Lim, Jae Nam, Joseph Sarver, Mukul Talaty. Robotic Arm (Orthosis) for Children with Muscular Dystrophy Modeling Human Response to Rough Terrain Ride Military and agricultural vehicles often subject their occupants to high crest vibrations and impulsive motion perturbations. The objective of this study is to assess the response of the spine to such motion, when muscular function exists and is contributory to the spinal loading. Reflection Of Muscle Exertion Level And Fatigue In Force Tremor Patterns: Physiological Modeling And Experimental Validation Weight Bearing Optimization in Prosthetic Limbs Lower limb prostheses are attached to the residual limb with a socket interface that transmits the forces of impact to the soft tissue and skeleton via specialized contact areas. The objective of this project is to determine the optimal geometry of the contact area, which in turn will produce minimal tissue overload and will minimize risk of pain and ulceration. Fatigue and muscular exertion may determine the likelihood of sustaining injuries in a workplace or while driving. The use of accelerometers or force sensors to determine the extent of fatigue may be a valuable, non-invasive tool for accident prevention. The objective of this study is to assess the validity of this technique and compare it with alternative tools, such as electromyography. PROGRAM OVERVIEWPROGRAM OVERVIEW

2. School of Biomedical Engineering, Science & Health Systems WWW.BIOMED.DREXEL.EDU/ResearchPortfolio/ V 1.0 SD [020118] ROBOTIC ARM (ORTHOSIS) FOR CHILDREN WITH MUSCULAR DYSTROPHY Children afflicted with muscular dystrophy loose function of their arms progressively. The objective of this project is to study the characteristics of the decline in muscle power and to develop a powered orthotic device that will enable them to continue to use their arms. Faculty: Rami Seliktar, Ph.D. E-mail: seliktar@coe.drexel.edu Collaborating Researchers: Tariq Rahman, Ph.D., AI duPont Hospital for Children and Alberto Esquenazi, M.D., Moss Rehabilitation Hospital Graduate Students: Roscoe Bowen, Riccardo Conti, Dohyung Lim, Jae Nam, Joseph Sarver, Mukul Talaty. PROJECTONEPAGERPROJECTONEPAGER

3. School of Biomedical Engineering, Science & Health Systems WWW.BIOMED.DREXEL.EDU/ResearchPortfolio/ V 1.0 SD [020118] MODELING HUMAN RESPONSE TO ROUGH TERRAIN RIDE Military and agricultural vehicles often subject their occupants to high crest vibrations and impulsive motion perturbations. The objective of this study is to assess the response of the spine to such motion, when muscular function exists and is contributory to the spinal loading. Faculty: Rami Seliktar, Ph.D. E-mail: seliktar@coe.drexel.edu Collaborating Researchers: Tariq Rahman, Ph.D., AI duPont Hospital for Children and Alberto Esquenazi, M.D., Moss Rehabilitation Hospital Graduate Students: Roscoe Bowen, Riccardo Conti, Dohyung Lim, Jae Nam, Joseph Sarver, Mukul Talaty. PROJECTONEPAGERPROJECTONEPAGER

4. School of Biomedical Engineering, Science & Health Systems WWW.BIOMED.DREXEL.EDU/ResearchPortfolio/ V 1.0 SD [020118] REFLECTION OF MUSCLE EXERTION LEVEL & FATIGUE IN FORCE TREMOR PATTERNS: PHYSIOLOGICAL MODELING & EXPERIMENTAL VALIDATION Fatigue and muscular exertion may determine the likelihood of sustaining injuries in a workplace or while driving. The use of accelerometers or force sensors to determine the extent of fatigue may be a valuable, non- invasive tool for accident prevention. The objective of this study is to assess the validity of this technique and compare it with alternative tools, such as electromyography. PROJECTONEPAGERPROJECTONEPAGER Faculty: Rami Seliktar, Ph.D. E-mail: seliktar@coe.drexel.edu Collaborating Researchers: Tariq Rahman, Ph.D., AI duPont Hospital for Children and Alberto Esquenazi, M.D., Moss Rehabilitation Hospital Graduate Students: Roscoe Bowen, Riccardo Conti, Dohyung Lim, Jae Nam, Joseph Sarver, Mukul Talaty.

5. School of Biomedical Engineering, Science & Health Systems WWW.BIOMED.DREXEL.EDU/ResearchPortfolio/ V 1.0 SD [020118] WEIGHT BEARING OPTIMIZATION IN PROSTHETIC LIMBS Lower limb prostheses are attached to the residual limb with a socket interface that transmits the forces of impact to the soft tissue and skeleton via specialized contact areas. The objective of this project is to determine the optimal geometry of the contact area, which in turn will produce minimal tissue overload and will minimize risk of pain and ulceration. Faculty: Rami Seliktar, Ph.D. E-mail: seliktar@coe.drexel.edu Collaborating Researchers: Tariq Rahman, Ph.D., AI duPont Hospital for Children and Alberto Esquenazi, M.D., Moss Rehabilitation Hospital Graduate Students: Roscoe Bowen, Riccardo Conti, Dohyung Lim, Jae Nam, Joseph Sarver, Mukul Talaty. PROJECTONEPAGERPROJECTONEPAGER