1. www.zfbiolabs.com BioSciencs Foro November 8th, New York

2. ZF Biolabs ZF Biolabs is a spanish biotechnology, established in 2003 and fully devoted to R&D activities in biomedicine and toxicology, working exclusively with zebrafish as the selected model organism.

3. ZF Biolabs Zebrafish use in Biomedical Research

4. ZF Biolabs i)Development of toxicity assays based on the use of the zebrafish embryo (develomental toxicity, neurotoxicity, cardiotoxicity, hepatotoxicity and short term toxicity). ii)Functional genomics: analysis of genes and phenotypes in zebrafish using morpholino oligonucleotide loss-of-function technique to study human diseases. iii)Development of new zebrafish supporting technologies aimed to improve the efficiency of embryo production. ZF Biolabs R&D

5. ZF Biolabs  Partner of the EU R&D Project Nuclear envelope-linked rare human diseases: from molecular pathophysiology towards clinical applications” coordinated by the Medical University of Vienna. T he role of ZF Biolabs is knocking down Lamin-A gene in zebrafish, screening for functional readouts of pathological phenotypes, identifying molecular drug targets and screening for new drugs.  Partner of the project “Role of FAAH in neuroprotection” in collaboration with Univ. of Salamanca, to develop a transgenic zebrafish model for discovering new neuroprotective drugs.  In collaboration with Canal de Isabel II, the public company in charge of managing the water in the Madrid region, ZF Biolabs is involved in the research project “Development of a new toxicity assay for detecting cyanotoxins in drinkable water using zebrafish embryos”. ZF BIOLABS COLLABORATIVE RESEARCH PROJECTS

6. ZF Biolabs ZF Biolabs is in contact with some USA Pharmaceutical companies, which are interested in the new toxicity assays and related zebrafish technology. ZF Biolabs will present its R&D results at the Health and Environmental Sciences Institute (HESI) Workshop on Alternative Assays For Developmental Toxicity, that will be held on February 27-28, 2007, in Cary (North Carolina). According to the possibility of collaboration with US companies ZF Biolabs will study alliances with established US companies and/or other alternatives. ZF Biolabs interest in USA