1. Healthy Purdue Stacey L. Mobley, PhD, RD, CNSD Assistant Professor Department of Foods and Nutrition A Platform for Research in Disease Prevention and Treatment The Purdue Health Initiative

2. Healthy Purdue The Purdue Health Initiative Reduce sick leave Improve employee satisfaction Lower health care costs Improve health care outcomes A wellness program to: Sponsored by Purdue Worklife Services

3. Eligibility: - Purdue Employees (Faculty, Staff, and Administrative) - Employee Spouses - Retirees - Retiree Spouses Benefits - Expanded health resources - Financial incentives for each participant Healthy Purdue The Purdue Health Initiative

4. Demographics of Participants Total = 8,991 Gender Employees 6,451 Females: 56% Males: 44% Employee Spouses 2,438 Retirees 89 Age Retiree Spouses 13 < 30 = 9% 30-39 = 19% Ethnicity 40-49 = 27% White or Other 87% 50-59 = 32% Asian, Hawaiian, or Pacific Islander 7% 60-69 = 11% Hispanic or Latino 2% 70 + = 2% Black or African American 2% American Indian or Alaska Native 1%

5. Healthy Purdue The Purdue Health Initiative  Height  Weight  Blood pressure  Blood glucose and cholesterol  Health risk assessment Results of the wellness screenings are used to identify moderate and high health risk participants Wellness Screenings

6. Healthy Purdue The Purdue Health Initiative Weight control Cholesterol Eating habits Physical activity Blood pressure Tobacco use Stress Alcohol Well being To reduce health risks, health coaching (behavioral therapy) is provided for……

7. Healthy Purdue Participants High Risk Low Risk Time With Outcome Screening & Intervention With Outcome BaselineYear 1Year 2 High Risk Low Risk Without Outcome Without Outcome Year n Screening & Intervention Screening & Intervention

8. Wellness Screening Results (HRA, Labs) MedStat Medical Claims Data (Expenditures, Diagnoses, Medications) Healthy Purdue The Purdue Health Initiative Purdue University

9. Healthy Purdue Unique Aspects for Research  Large sample size  Data set contains medical expenditures and clinical outcomes information on a “normal” population  Diet and lifestyle behavioral (habits) assessments  “Omic” capabilities at Purdue

10.  Lifestyle, Nutrition, and Behavioral Risk Factors in the Workplace: A Baseline Analysis of a Large Cohort Study  Changes in Nutrition and Lifestyle Behaviors in Response to Health Promotion in the Workplace  Cancer Care Engineering Approaches for Cancer Prevention, Diagnosis, and Treatment  Novel Proteomic Approaches for Early Detection of Metabolic Syndrome in Obese Adults Selected Research Projects Related to Healthy Purdue

11. Healthy Purdue Cohort (n = 8,991) Measurements/Data Collected - Health Risk Appraisal Survey (diet, physical activity, lifestyle behaviors, etc.) - Blood glucose and lipids; height; weight - Medical history - Medical diagnostic codes (disease diagnosis) - Medication codes (medication usage) - Hospital Admissions - Disabilities Ancillary Research Studies Measurements - Anthropometry - Diet History Questionnaires - Blood biomarkers (genes, proteins, metabolites) - Survey Questionnaires - Additional Clinical Data Enroll into Research Study Purdue Research Database Warehouse (RCHE) Individualized Medicine to Prevent and Treat Chronic Diseases Based On Metabolic and Behavioral Profiles Consolidate Data Data Analysis and Modeling Workflow Model for Translational Research in Chronic Disease Prevention and Treatment

12. A Forecast into the Future: Individualized Prescriptions to Prevent and Treat Chronic Disease…

13. Questions ?