1. E. Simko WCVM

2. PTT slides: http://duke.usask.ca/~els920/ *

3. References: General: Thomson's Special Veterinary Pathology W. W. Carlton et. al. Special: Muller & Kirk's Small Animal Dermatology D. W. Scott et. al Canine & Feline Dermatology G. H. Nesbitt and L. J. Ackerman Large Animal Dermatology D. W. Scott E. Simko WCVM

4. Dermis Epidermis Primary hair Secondary hair Superficial plexus Elector pili muscle Sebaceous gland Middle plexus Deep plexus Sweat gland E. Simko WCVM Subcutis

5. Infundibulum Isthmus Inferior segment Hair bulb Dermal papilla Hair Anatomy E. Simko WCVM

6. Stratum basale Basment membrane Stratum spinosum Stratum cornium Stratum granulosum Hemidesmosomes Desmosomes E. Simko WCVM Anatomy

7. Anatomy - Epidermis E. Simko WCVM Melanocytes Langerhans cells Merkel cells Lymphocytes

8. Exogenous Factors: Infectious Nutritional Allergic Physical Chemical Endogenous Factors: Immunologic Hereditary Congenital Hormonal Metabolic Emotional Internal dz Age E. Simko WCVM

9. Response to injury Orthokeratotic Hyperkeratosis Idiopathic seborrhea Ichtiosis Vitamin A deficiency E. Simko WCVM

10. Zinc-responsive dermatosis Hepatocutaneous syndrome E. Simko WCVM Parakeratotic Hyperkeratosis Response to injury

11. Irregular Regular Papillated Pseudocarcinomatous E. Simko WCVM Response to injury

12. Response to injury - Hyperplasia Pseudocarcin omatous PapillatedRegular Irregular Normal Hyperplasia Atrophy/ Hypoplasia Normal Aplasia E. Simko WCVM

13. Response to injury Hyperpigmentation Endocrine diseases Chronic inflammation E. Simko WCVM

14. Dermis Epidermis Response to injury Hypopigmentation Hereditary/Congenital Aquired with pigmentary incontinence E. Simko WCVM

15. Physiologic Pathologic (Programmed cell death) cell death initiating inflammation E. Simko WCVM Response to injury

16. Intercellular (Spongiosis) Non specific inflammatory change E. Simko WCVM Response to injury

17. Intracellular Edema Vacuolar degeneration Hydropic degeneration Balooning degeneration E. Simko WCVM Response to injury

18. Vesicle/pustule formation (Autoimmune dz) Reticular degeneration (Viral diseases) E. Simko WCVM Response to injury

19. E. Simko WCVM Autoimmune dz Pyoderma Response to injury Acanthocyte

20. E. Simko WCVM Exocytosis Pustule Crust (serous hemorrhgic, cellular) Response to injury

21. E. Simko WCVM Atrophy Inflammation and fibrosis Depositions Response to injury

22. E. Simko WCVM Atrophy Physiologic Pathologic Response to injury

23. Anagen Telogen Catagen Controlled by: daylight hours environment genetic factors hormones Modified from Applied Veterinary Histology, W.J.Banks

24. Modified from Applied Veterinary Histology, W.J.Banks and Small Animal Dermatology, D.W. Scott AnagenTelogen Response to injury

25. Superficial folliculitis Deep folliculitis Furunculosis Adenitis E. Simko WCVM Response to injury