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Corneal collagen cross-linking (CXL) ALIREZA PEYMAN, MD ISFAHAN UNIVERSITY OF MEDICAL SCIENCES.

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Presentation on theme: "Corneal collagen cross-linking (CXL) ALIREZA PEYMAN, MD ISFAHAN UNIVERSITY OF MEDICAL SCIENCES."— Presentation transcript:

1 http://www.drpeyman.ir Corneal collagen cross-linking (CXL) ALIREZA PEYMAN, MD ISFAHAN UNIVERSITY OF MEDICAL SCIENCES

2 http://www.drpeyman.ir CXL with riboflavin and ultraviolet-A irradiation introduced in 1998 Spoerl E, Huhle M, Seiler T. Induction of cross-links in corneal tissue. Exp Eye Res. 1998;66:97–103.

3 http://www.drpeyman.ir Indications  Cornea ectasias  KC  PMD  Iatrogenic ectasias  Post-LASIK keratectasia  Infectious ulcers  Corneal edema

4 http://www.drpeyman.ir Importance of age of the patient  <10 years old    10-20 years   20-30  30-40  >40 

5 http://www.drpeyman.ir Technique  Using a wavelength of 370 nm with an accumulated irradiance of 5.4 J/cm 2 ensures that the exposure of all structures is below harmful levels

6 http://www.drpeyman.ir  Epi-Off  Epi-On Penetration of riboflavin Role of oxygen

7 http://www.drpeyman.ir Irradiation  Conventional  Accelerated  Pulsed

8 http://www.drpeyman.ir Complications  Significant haze  CTK  Infection

9 http://www.drpeyman.ir Combinations  CXL + ICRS  CXL + Microwave keratoplasty (Keraflex)  CXL + PRK  CXL + LASIK

10 http://www.drpeyman.ir Is repeat CXL helpful?

11 http://www.drpeyman.ir

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