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Objectives: Name the four major tissue types and their subcategories
Explain how each type of tissue is classified Relate each types structure to the function it performs in the body What are the common characteristics for each tissue type
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Jigsaw activity Aces: Explain classification of Epithelial tissue (page 78-79) Kings: Characteristics of Epithelial tissue Queens: Simple Epithelial (subcategories, function and location) Jacks: Stratified Epithelial (subcategories, function and location) Tens: Glandular Epithelium (subcategories, function and location)
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Body Tissues Cells are specialized for particular functions Tissues
Groups of cells with similar structure and function Four primary types Epithelium Connective tissue Nervous tissue Muscle Slide 3.41 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
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Epithelial Tissues Found in different areas Functions Body coverings
Body linings Glandular tissue Functions Protection Absorption Filtration Secretion Slide 3.42 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
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Epithelium Characteristics
Cells fit closely together (Sheet Like) Tissue layer always has one free surface The lower surface is bound by a basement membrane Avascular (have no blood supply) Regenerate easily if well nourished Slide 3.43 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
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Classification of Epithelium
Number of cell layers Simple – one layer Stratified – more than one layer Figure 3.16a Slide 3.44a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
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Classification of Epithelium
Shape of cells Squamous – flattened Cuboidal – cube-shaped Columnar – column-like Figure 3.16b Slide 3.44b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
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Simple Epithelium Simple squamous Single layer of flat cells
Usually forms membranes Lines body cavities Lines lungs and capillaries Figure 3.17a Slide 3.45 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
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Squamous The epithelium is a single layer of flat, or squamous, cells.
The peripheral cytoplasm of each cell is so attenuated that it is usually not resolvable; the nucleus is usually the only cellular structure visible. The nucleus usually has a flattened appearance (sometimes spherical), and, due to the width of the cells, nuclei of adjacent cells are usually separated by a distance of many nuclear diameters. The cells' surfaces are void of specialized surface structures, such as cilia or microvilli.
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Basement membrane
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Apical surface Basement membrane
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Simple Epithelium Simple cuboidal Single layer of cube-like cells
Common in glands and their ducts Forms walls of kidney tubules Covers the ovaries Figure 3.17b Slide 3.46 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
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Cuboidal This epithelium consists of a single layer of cuboidal cells resting on an undetectable basement membrane. The height of each epithelial cell is nearly equal to the width of the cell. The cells are tightly packed, forming a continuous sheet of cells that effectively forms the wall of a kidney tubule. The nucleus is spherical and sits at the near-center of the cell. The nuclei of adjacent cells are relatively close together, certainly closer than in a simple squamous epithelium, and are aligned in a single row.
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Simple Epithelium Simple columnar Single layer of tall cells
Often includes goblet cells, which produce mucus Lines digestive tract Figure 3.17c Slide 3.47 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
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Cuboidal The epithelium consists of a single layer of columnar cells (the cells' height is significantly greater then their width) resting on an undetectable basement membrane. The cells are tightly packed, forming a continuous sheet of cells that effectively forms the protective lining of the stomach. The nucleus is generally ovoid and sits at the lower to mid-portion of the cell. Because the width of the cell is relatively narrow, the nuclei of adjacent cells are relatively close together and are aligned in a single row.
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Fig. 2. Mammalian stomach (H & E).
Lu, stomach lumen LuS, lumenal surface. Epi, simple secretory columnar epithelium
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Simple Epithelium Pseudostratified
Single layer, but some cells are shorter than others Often looks like a double cell layer Sometimes ciliated, such as in the respiratory tract May function in absorption or secretion Figure 3.17d Slide 3.48 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
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Pseudostratified The nuclei staggered, while not obvious, all the epithelial cells in this membrane rest on the basement membrane, but they vary in height - all do not reach the apical surface. This contributes to the staggered locations of the nuclei. Note the ciliated border of the columnar cells. Cilia are relatively flexible, motile hair-like surface projections. The cilia of the respiratory epithelium beat constantly toward the pharynx and nasal passages, creating a continuous flow of mucus in that direction. Note the presence of goblet cells. While individual goblet cells are seldomly distinct, a mucus cup can occasiionally be seen. Tracheal goblet cells secret mucus over the surface of the epithelium to prevent dessication and to trap air-borne microscopic particulates, thus cleansing air as it passes to the lung alveoli.
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Stratified Epithelium
Stratified squamous Cells at the free edge are flattened Found as a protective covering where friction is common Locations Skin Mouth Esophagus Figure 3.17e Slide 3.49 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
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Stratified Epithelium
Stratified cuboidal (RARE) a) When found, you see it as two layers of cuboidal cells b) Ducts (sweat glands, mammary glands). Stratified columnar (very limited in distribution) *Present in Large ducts of some glands* Pharynx, male urethra, and lining some glandular ducts. Slide 3.50 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
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Stratified Epithelium
Transitional epithelium Shape of cells depends upon the amount of stretching Lines organs of the urinary system (Ureters, urinary bladder, part of the urethra) Figure 3.17f Slide 3.51 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
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Glandular Epithelium Gland – one or more cells that secretes a particular product Two major gland types Endocrine gland Ductless Secretions are hormones Exocrine gland Empty through ducts to the epithelial surface Include sweat and oil glands Slide 3.52 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
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