1. September 5-8, 2013

2. What are these? Tissues!

3. Epithelial Tissue – Epithelial Tissue – lining, covering, & glandular lining, covering, & glandular Connective – Connective – protecting, supporting, and binding together protecting, supporting, and binding together Muscular – movement Muscular – movement Nervous - control Nervous - control

4. Epithelial tissues lines all body surfaces and cavities Functions: protection protection absorption absorption filtration filtration secretion secretion

5. Special features of epithelial tissue: Cells are tightly bound together Cells are tightly bound together Basal surface attached to basement membrane, apical surface is free. Basal surface attached to basement membrane, apical surface is free. Avascular – no blood supply. Nutrition and gases diffuse from underlying connective tissue Avascular – no blood supply. Nutrition and gases diffuse from underlying connective tissue Excellent regenerative ability. Contain multi- and uni-potent stem cells. Excellent regenerative ability. Contain multi- and uni-potent stem cells.

6. Turn & Talk: How does each special feature relate to the functions of epithelial tissue? - 2 min

7. Basic Shapes

8. Simple squamous epithelium Simple squamous epithelium A single layer of thin cells, specializing in rapid diffusion and filtration Found in: alveoli of lungs, walls of capillaries, kidney glomeruli and serosae

9. Simple squamous epithelium Simple squamous epithelium A single layer of thin cells, specializing in rapid diffusion and filtration Found in: alveoli of lungs, walls of capillaries, kindey glomeruli, and serosae Picture of alveoli of lungs.

10. Simple cuboidal epithelium Simple cuboidal epithelium A single layer of cube- shaped cells Found in: glands, kidney tubules, ovaries Kidney tubules

11. Simple columnar epithelium Simple columnar epithelium A single layer of tall shaped cells Often contain mucus- Goblet cells producing Goblet cells and / or cilia and / or cilia Found in: digestive tract (unciliated), bronchi (ciliated), and uterine tubes (ciliated) Small intestine

12. Simple columnar epithelium Simple columnar epithelium A single layer of tall shaped cells Often contain mucus- Goblet cells producing Goblet cells and / or cilia and / or cilia Found in: digestive tract (unciliated), bronchi (ciliated), and uterine tubes (ciliated) Uterine tube

13. Pseudostratified columnar epithelium Pseudostratified columnar epithelium A single layer of cells that differ in length. Often contain cilia and Goblet cells Found in: respiratory tract trachea

14. Pseudostratified columnar epithelium Pseudostratified columnar epithelium A single layer of cells that differ in length. Often contain cilia and Goblet cells Found in: respiratory tract trachea Notice that the nuclei appear at different levels. For our purposes: nuclei at different levels + cilia = pseudostratified columnar epithelia

15. Stratified Squamous Epithelium Stratified Squamous Epithelium Multiple layers of epithelial tissue. Flattened and atrophied (‘dead’) at the apical edge; but can be rounder at basal edge. Apical edge sloughs off and is replaced. Esophagus? Function: protection from wear & tear Found in skin, mouth, esophagus

16. Transitional epithelium Transitional epithelium Cells can change shape, allowing the tissue to stretch. Apical cells appear round when tissue is relaxed, and flat with tissue is stretched. Found in urinary tract. Ureter tube

17. Transitional epithelium Transitional epithelium Cells can change shape, allowing the tissue to stretch. Apical cells appear round when tissue is relaxed, and flat with tissue is stretched. Found in urinary tract. Ureter tube Notice that the cells look rounded and irregular.

18. Show with fingers: 1) Simple squamous 2) Simple cuboidal 3) Simple columnar 4) Stratified squamous 5) Transitional

19. Show with fingers: 1) Simple squamous 2) Simple cuboidal 3) Simple columnar 4) Stratified squamous 5) Transitional Notice the cube-like shapes, and single layers separated by basement membrane

20. Show with fingers: 1) Simple squamous 2) Simple cuboidal 3) Simple columnar 4) Stratified squamous 5) Transitional

21. Show with fingers: 1) Simple squamous 2) Simple cuboidal 3) Simple columnar 4) Stratified squamous 5) Transitional Notice the many layers, and how the cells gradually become flatter

22. Show with fingers: 1) Pseudostratified columnar 2) Simple cuboidal 3) Simple columnar 4) Stratified squamous 5) Transitional

23. Show with fingers: 1) Pseudostratified columnar 2) Simple cuboidal 3) Simple columnar 4) Stratified squamous 5) Transitional Notice multiple layers, cells rounded and irregular

24. Show with fingers: 1) Pseudostratified columnar 2) Simple cuboidal 3) Simple columnar 4) Stratified squamous 5) Transitional

25. Show with fingers: 1) Pseudostratified columnar 2) Simple cuboidal 3) Simple columnar 4) Stratified squamous 5) Transitional Notice the nuclei at different levels, and the cilia

26. Examine the following tissues under a microscope: Simple cuboidal (kidney tubule) Simple columnar (uterine tube?) Stratified squamous (skin) Transitional (bladder?) Pseudostratified columnar (trachea?) As you observe these, create a histology guide by sketching each tissue (USE COLOR & LABEL IMPORTANT FEATURES). Jotting down any notes that will help you identify the tissue in the future Use your textbook to list both the FUNCTIONS and LOCATIONS of the tissues. Spend the time to do this right!! Draw carefully and accurately. Use color. Compare to your textbook. ASK FOR HELP IF YOU AREN’T SURE IF YOU ARE SEEING IT! You will get to use these notes on a lab practical!