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Structure-Based Design of Supercharged, Highly Thermoresistant Antibodies Aleksandr E. Miklos, Christien Kluwe, Bryan S. Der, Supriya Pai, Aroop Sircar,

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Presentation on theme: "Structure-Based Design of Supercharged, Highly Thermoresistant Antibodies Aleksandr E. Miklos, Christien Kluwe, Bryan S. Der, Supriya Pai, Aroop Sircar,"— Presentation transcript:

1 Structure-Based Design of Supercharged, Highly Thermoresistant Antibodies Aleksandr E. Miklos, Christien Kluwe, Bryan S. Der, Supriya Pai, Aroop Sircar, Randall A. Hughes, Monica Berrondo, Jianqing Xu, Vlad Codrea, Patricia E. Buckley, Alena M. Calm, Heather S. Welsh, Candice R. Warner, Melody A. Zacharko, James P. Carney, Jeffrey J. Gray, George Georgiou, Brian Kuhlman, Andrew D. Ellington Chemistry & Biology Volume 19, Issue 4, Pages 449-455 (April 2012) DOI: 10.1016/j.chembiol.2012.01.018 Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

2 Figure 1 Chemistry & Biology 2012 19, 449-455DOI: (10.1016/j.chembiol.2012.01.018) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

3 Figure 2 Chemistry & Biology 2012 19, 449-455DOI: (10.1016/j.chembiol.2012.01.018) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

4 Figure 3 Chemistry & Biology 2012 19, 449-455DOI: (10.1016/j.chembiol.2012.01.018) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions


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