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TIMETABLE 1 BIOINFORMATICS_14 (Advanced Biological Chemistry) 1. Introductory remarks on biochemical information resources.

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Presentation on theme: "TIMETABLE 1 BIOINFORMATICS_14 (Advanced Biological Chemistry) 1. Introductory remarks on biochemical information resources."— Presentation transcript:

1 TIMETABLE 1 BIOINFORMATICS_14 (Advanced Biological Chemistry) 1. Introductory remarks on biochemical information resources

2 2

3 Assisted by: Andrea Bernini andrea.bernini@unisi.itandrea.bernini@unisi.it Ottavia Spiga ottavia.spiga@unisi.itottavia.spiga@unisi.it Simone Gardini simone_gardini@hotmail.comsimone_gardini@hotmail.com Powerpoint slides to be downloaded from: http://www.sienabiografix.it/edu BIOINFORMATICS_14 (Advanced Biological Chemistry) Academic year 2014-2015 Neri Niccolai 3 1. Introductory remarks on biochemical information resources

4 4 BIOINFORMATICS_14 (Advanced Biological Chemistry) http://www.sienabiografix.it/edu

5 5 syllabus: 1.Introductory remarks on biochemical information resources 2.Nucleic acids and proteins in one and more dimensions 3.Retrieving information from nucleotide and amino acid sequences 4.3D structure predictions of RNAs and proteins 5.Bioinformatics for pathogen protection 6.Practicals on Immuno-Bioinformatics BIOINFORMATICS_14 1. Introductory remarks on biochemical information resources written test

6 6 TEXTBOOK BIOINFORMATICS_14 1. Introductory remarks on biochemical information resources

7 7 TEXTBOOK BIOINFORMATICS_14 1. Introductory remarks on biochemical information resources

8 Automatic procedures Robotics exploring Life in post-genomic era 8 1. Introductory remarks on biochemical information resources

9 Databank 1 Databank 2 Databank 4 Databank 5 Databank 3 Databank n Bioinformatics Bioknowledge huge amount of data distributed in databank exploring Life in post-genomic era 9 1. Introductory remarks on biochemical information resources

10 10 1. Introductory remarks on biochemical information resources exploring Life in post-genomic era

11 11 1. Introductory remarks on biochemical information resources exploring Life in post-genomic era databanks+Bioinformatics= biological knowledge

12 Bioinformatics genome + algorithm * Sequence Alignment Gene localization Genome reconstruction from fragments Protein structure alignment protein structure prediction prediction of gene expression prediction of protein-protein interaction * algorithm = an algorithm is a step-by-step procedure for calculations. Algorithms are used for calculation, data processing, and automated reasoning. An algorithm is an effective method expressed as a finite list of well-defined instructions for calculating a function. 12 2. Nucleic acids and proteins in one and more dimensions

13 millions or billions of times 13 (deoxy)nucleotide base DNA 4 bases base TACTG…… 1. Introductory remarks on biochemical information resources

14 From tens to thousands 14 RNA 4 bases base Uracil U 1. Introductory remarks on biochemical information resources

15 15 1. Introductory remarks on biochemical information resources

16 16 1. Introductory remarks on biochemical information resources

17 hydrogen carbon oxygen sulphur nitrogen amino acid + 1 2 …… …… 3 M L K 4 A 5 W 6 R 7 F 8 D 9 Q Thousands of times more often 100 - 500 17 1. Introductory remarks on biochemical information resources

18 18 1. Introductory remarks on biochemical information resources

19 19 http://www.slideshare.net/BlazeDreamTech/website-vs-portal 1. Introductory remarks on biochemical information resources

20 20 1. Introductory remarks on biochemical information resources

21 21 1. Introductory remarks on biochemical information resources Guided tour of NCBI portal

22 22 1. Introductory remarks on biochemical information resources Guided tour of NCBI portal

23 23 1. Introductory remarks on biochemical information resources Guided tour of NCBI portal

24 24 1. Introductory remarks on biochemical information resources Guided tour of NCBI portal

25 25 1. Introductory remarks on biochemical information resources Guided tour of NCBI portal

26 26 1. Introductory remarks on biochemical information resources Guided tour of NCBI portal

27 27 1. Introductory remarks on biochemical information resources Guided tour of NCBI portal

28 28 1. Introductory remarks on biochemical information resources Guided tour of NCBI portal

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