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This article and any supplementary material should be cited as follows: Riechers RG, Shuster JL, Bryan KJ, Burant C, Ball SL. Prior housing conditions.

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Presentation on theme: "This article and any supplementary material should be cited as follows: Riechers RG, Shuster JL, Bryan KJ, Burant C, Ball SL. Prior housing conditions."— Presentation transcript:

1 This article and any supplementary material should be cited as follows: Riechers RG, Shuster JL, Bryan KJ, Burant C, Ball SL. Prior housing conditions and sleep loss may affect recovery from brain injury in rats: A pilot study. J Rehabil Res Dev. 2013;50(4):455–62. http://dx.doi.org/10.1682/JRRD.2012.04.0061 Slideshow Project DOI:10.1682/JRRD.2012.04.0061JSP Prior housing conditions and sleep loss may affect recovery from brain injury in rats: A pilot study Ronald G. Riechers, MD; Jaime L. Shuster, MA; Kathryn J. Bryan, PhD; Christopher Burant, PhD; Sherry L. Ball, PhD

2 This article and any supplementary material should be cited as follows: Riechers RG, Shuster JL, Bryan KJ, Burant C, Ball SL. Prior housing conditions and sleep loss may affect recovery from brain injury in rats: A pilot study. J Rehabil Res Dev. 2013;50(4):455–62. http://dx.doi.org/10.1682/JRRD.2012.04.0061 Slideshow Project DOI:10.1682/JRRD.2012.04.0061JSP Aim – Understand effect of combat-associated conditions such as sleep deprivation (SD) on subsequent traumatic brain injury (TBI). Relevance – Combat operations are associated with high stress and prolonged SD. – TBI is signature injury of conflicts in Iraq and Afghanistan.

3 This article and any supplementary material should be cited as follows: Riechers RG, Shuster JL, Bryan KJ, Burant C, Ball SL. Prior housing conditions and sleep loss may affect recovery from brain injury in rats: A pilot study. J Rehabil Res Dev. 2013;50(4):455–62. http://dx.doi.org/10.1682/JRRD.2012.04.0061 Slideshow Project DOI:10.1682/JRRD.2012.04.0061JSP Method Tested 4 groups of rats: – 24 h of SD in isolation followed by TBI (SD+CCI). – No SD in isolation followed by TBI (no SD+CCI). – Normal housing followed by TBI. – Normal housing and no TBI. Tested rats with beam walk test and adhesive removal test at baseline and 4, 7, and 14 days after TBI.

4 This article and any supplementary material should be cited as follows: Riechers RG, Shuster JL, Bryan KJ, Burant C, Ball SL. Prior housing conditions and sleep loss may affect recovery from brain injury in rats: A pilot study. J Rehabil Res Dev. 2013;50(4):455–62. http://dx.doi.org/10.1682/JRRD.2012.04.0061 Slideshow Project DOI:10.1682/JRRD.2012.04.0061JSP Results SD+CCI group: – Earlier recovery than no SD+CCI group. No SD+CCI group: – Recovered slower than all other groups. Data suggest that: – 24 h of preinjury SD results in faster recovery. – Novel or social isolation conditions impedes recovery.

5 This article and any supplementary material should be cited as follows: Riechers RG, Shuster JL, Bryan KJ, Burant C, Ball SL. Prior housing conditions and sleep loss may affect recovery from brain injury in rats: A pilot study. J Rehabil Res Dev. 2013;50(4):455–62. http://dx.doi.org/10.1682/JRRD.2012.04.0061 Slideshow Project DOI:10.1682/JRRD.2012.04.0061JSP Conclusion Combat environment may contribute to complexities associated with TBIs common in U.S. servicemembers.

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