1. INFECTIOUS DISEASE IN HISTORY IMAGES

2. Watercolour illustration from a Japanese work on smallpox entitled Toshin seiyo (‘The essentials of smallpox’), consisting of a manuscript in two volumes. According to the beginning of book two, the author was Kanda Gensen (c 1670–1746). c.1720. Credit: Wellcome Library, London Japanese illustration of smallpox

3. The face of a man with smallpox, and a vaccination against smallpox. Colour process print, c.1940. Credit: Wellcome Library, London BIGPICTUREEDUCATION.COM Spanish-language smallpox poster

4. Edward Jenner performing his first vaccination on a child, 1796. Oil painting by Ernest Board, 1920s. Credit: Wellcome Library, London BIGPICTUREEDUCATION.COM Edward Jenner

5. Left arm showing smallpox (left) and cowpox (right) inoculations on day 15. Two of a series of 30 comparative watercolours of smallpox and cowpox inoculation. By George Kirtland, 1802.George Kirtland Credit: Wellcome Library, London BIGPICTUREEDUCATION.COM Smallpox inoculation

6. Inside the cardboard is a small thin glass tube containing a single vaccine for smallpox. Made from calf lymph by the Jenner Institute for Calf Lymph Ltd, the vaccine has been sealed in glycerine so it can be easily transported over long distances. Calves were injected with smallpox, and lymph material from the pus caused by the disease was used as a vaccine. Credit: Science Museum, London/Wellcome ImagesScience Museum, London BIGPICTUREEDUCATION.COM 1920s vaccination kit

7. A giant mosquito trying to attack a French soldier who is protected by a mosquito net. Colour lithograph after H Stephany, 1917. Credit: Wellcome Library, London BIGPICTUREEDUCATION.COM French-language malaria poster

8. Mosquito net Postcard showing a mosquito net to be worn as a veil. Early 20th century. Credit: Wellcome Library, London BIGPICTUREEDUCATION.COM

9. Sir Alexander Fleming (1881–1955), who discovered the antibiotic penicillin. Credit: Wellcome Library, London BIGPICTUREEDUCATION.COM Sir Alexander Fleming

10. Reusing our images Images and illustrations All images, unless otherwise indicated, are from Wellcome Images. Contemporary images are free to use for educational purposes (they have a Creative Commons Attribution, Non-commercial, No derivatives licence). Please make sure you credit them as we have done on the site; the format is ‘Creator’s name, Wellcome Images’.Creative Commons Attribution, Non-commercial, No derivatives licence Historical images have a Creative Commons Attribution 4.0 licence: they’re free to use in any way as long as they’re credited to ‘Wellcome Library, London’.Creative Commons Attribution 4.0 licence Flickr images that we have used have a Creative Commons Attribution 4.0 licence, meaning we – and you – are free to use in any way as long as the original owner is credited.Creative Commons Attribution 4.0 licence Cartoon illustrations are © Glen McBeth. We commission Glen to produce these illustrations for ‘Big Picture’. He is happy for teachers and students to use his illustrations in a classroom setting, but for other uses, permission must be sought. We source other images from photo libraries such as Science Photo Library, Corbis and iStock and will acknowledge in an image’s credit if this is the case. We do not hold the rights to these images, so if you would like to reproduce them, you will need to contact the photo library directly. If you’re unsure about whether you can use or republish a piece of content, just get in touch with us at bigpicture@wellcome.ac.uk.bigpicture@wellcome.ac.uk