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Pensamientos sobre FDR Alberto Medina 10 th, Dec. 2012.

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Presentation on theme: "Pensamientos sobre FDR Alberto Medina 10 th, Dec. 2012."— Presentation transcript:

1 Pensamientos sobre FDR Alberto Medina 10 th, Dec. 2012

2 FDR. ¿Protein or Peptide?

3 How we define an experiment?

4 Missed entries

5 False positives ¿FDR por Fracción o Experimento?

6 12 exp. Grouping by experiment

7 12 exp. Grouping by cell line (3)

8 Chr16 proteins. NO FDR 388pr/319.

9 1 exp = 10 searches FDR 1% protein. 292/239 (genes).

10 1 exp = 1 search (10 exps). FDR 1% protein. 316/260

11 Sensivity

12 1 exp = 1 search (10 exps). FDR 1% protein. 316/260

13 1 exp = 1 search (10 exps). FDR 1% peptide. 336/279


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