1. DO NOW: List 3 things you have learned about Selective Breeding Dolly Objective: Learn the Process of Cloning and What the Benefits and Concerns Are New Words: clone, cloning, embryo, donor organism, foster organism

2. Dolly 1. What do you already know about “Cloning”? Objective: Learn the Process of Cloning and What the Benefits and Concerns Are New Words: clone, cloning, embryo, donor organism, foster organism

3. http://learn.genetics.utah.edu/content/tech/cloning/clickandclone/ Cloning is the creation of an organism that is an exact genetic copy of another. This means that every single bit of DNA is the same between the two! Dolly 2. What exactly is Cloning? Objective: Learn the Process of Cloning and What the Benefits and Concerns Are New Words: clone, cloning, embryo, donor organism, foster organism

4. 3. Arrange the following steps in order from 1 through 7. A donor cell is taken from a sheep’s udder. Donor Nucleus These two cells are fused using an electric shock. Fused Cell The fused cell begins dividing normally. Embryo The embryo is placed in the uterus of a foster mother. Foster Mother The embryo develops normally into a lamb—Dolly Cloned Lamb Egg Cell An egg cell is taken from an adult female sheep. The nucleus of the egg cell is removed. The fused cell begins dividing, becoming an embryo. ____________ The embryo develops into a cloned animal ____________________ An egg cell is taken from a donor animal ______________________ The embryo is implanted into the uterus of a foster mother. _______ The body cell and egg are fused by electric shock. ______________ A body cell is taken from a donor animal ______________________ The nucleus is removed from the egg. ________________________ Objective: Learn the Process of Cloning and What the Benefits and Concerns Are New Words: clone, cloning, embryo, donor organism, foster organism 1 4 3 6 2 5 7

5. Test your cloning savvy with this interactive quiz. http://learn.genetics.utah.edu/content/tech/cloning/cloningornot/ Dolly 4. Is it Cloning? Or not? Objective: Learn the Process of Cloning and What the Benefits and Concerns Are New Words: clone, cloning, embryo, donor organism, foster organism

6. Species cloned Tadpole: (1952) Carp: (1963) Mice: (1986) Sheep: (1996) MOLLY Rhesus Monkey: (January 2000) Gaur: (2001) Cattle: (males, 2001) and (2005) Cat: (2004) Dog: (2005) Rat: first cloned rat (2003) Mule: 2003 Horse: 2003 Water Buffalo: 2009 Camel: (2009) Objective: Learn the Process of Cloning and What the Benefits and Concerns Are New Words: clone, cloning, embryo, donor organism, foster organism

7. a. What is a clone? 3. List two benefits of cloning: 4. List two concerns of cloning: 5. What kinds of mammals have been cloned in recent years? 6. Why do not scientists clone humans? A member of a population of genetically identical cells produced from a single cell a) It may help to save endangered species b) It makes copies of transgenic animals a)Cloned animals may suffer from a number of genetic defects b)Cloned animals may have health problems Sheep, cows, pigs, mice, horse,… Many people oppose the cloning of humans because ethical, moral, and religious reasoning Objective: Learn the Process of Cloning and What the Benefits and Concerns Are New Words: clone, cloning, embryo, donor organism, foster organism

8. Objective: Summarize the main ideas about Cloning New Words: clone, cloning, embryo, donor organism, foster organism What are the concerns? How humans have benefited from this technique Specific examples of how this technique has been used Brief description of what is involved in the technique CLONING Name of the Technique

9. a) It may help to save endangered species b) It makes copies of transgenic animals a)Cloned animals may suffer from a number of genetic defects b)Cloned animals may have health problems Sheep, cows, pigs, mice, horse, etc. have been cloned Objective: Summarize the main ideas about Cloning New Words: clone, cloning, embryo, donor organism, foster organism What are the concerns? How humans have benefited from this technique Specific examples of how this technique has been used Brief description of what is involved in the technique CLONING Name of the Technique process of producing genetically identical individuals

10. 1. From a single monkey, an animal breeder claims that he has successfully cloned two monkeys. He displays the two monkeys, a male and a female, to the public. The claim of the breeder should be rejected because 2. Write a paragraph in which you express you opinion about cloning human beings. The two monkeys are not genetically identical, they show different sex genders. Objective: Practice Regent’s Questions about Cloning New Words: clone, cloning, embryo, donor organism, foster organism