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Copyright © 2009 Recombinant Data Corp. All rights reserved. Ontology Query Composer CRC p2s PM.

Published byPeregrine Newton Modified over 9 years ago

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Presentation on theme: "Copyright © 2009 Recombinant Data Corp. All rights reserved. Ontology Query Composer CRC p2s PM."— Presentation transcript:

1 Copyright © 2009 Recombinant Data Corp. All rights reserved. Ontology Query Composer CRC p2s PM

2 2 U Mass Medical School: MICARD Sample Data snp/genetics, cDNA, assays, location Integrated clinical research platform Bench Bedside Consent mgr. HIPAA Bio-repository Consent Clinicians Patient care IT Researchers Clinical Data Diagnoses, Medications, Lab results

3 3 Recombinant sample related initiatives Direct projects – UMass Medical School consented bio-repository – HSSC consent management GO grant – Pharma clinical trials/Biobank interface New initiatives – SPIN - PSL/SHRINE and i2b2 synchronization – CTSA Biobank consortia – caTissue/i2b2 integration sites – Emerging discarded blood sample projects

4 4 Blood (Lab) Blood (Lab) Tissue (caTissue) Tissue (caTissue) Blood (Biobank) Blood (Biobank) Tissue (PSL) Tissue (PSL) Phenotype (i2b2 clinical data) prospectiveretrospective +/- consent + consent +/- consent p2s connector scenarios patient Biomarkers (‘omics and images) Biomarkers (‘omics and images) p2s

5 5 p2s integration points

6 6 Strategic Objectives Full compatibility with i2b2 license model Minimize redundancy – Other projects – Redundant components Adopt and extend existing resources – SHRINE/SPIN/PSL – i2b2 & web client framework – Recombinant projects – Open source development collaborations

7 7 p2s connector - Components

8 8

9 9 i2b2 Query

10 10 p2s connector biorepository adapter

11 11 p2s connector biorepository adapter

12 12 p2s connector biorepository adapter

13 13

14 14 p2s connector fulfillment

15 15 “highly effective” expression profiling from old

16 16 p2s connector PSL adapter

17 17 p2s connector PSL adapter

18 18 Modeling sample flow and request response

19 19 p2s connector request manager

20 20 p2s connector request manager

21 21 p2s connector request tracker

22 22 Next steps Contribute existing code to open source project Establish project teams/collaborations/governance Build-out new components Grants or projects for establishing new capabilities Biomarker downstream linkage strategy Questions?

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