1. Chronic Eosinophilic Pneumonia As Presented by Brett W. Baskovich…

2. What is it? Pneumonia Eosinophilic Chronic

4. Causes of Eosinophilic Pneumonia Churg-Strauss Syndrome Allergic Bronchopulmonary Aspergillosis Medications/Drugs/Toxins –N–N–N–Nitrofurantoin, ampicillin, ibuprofen, naproxen, phenytoin, sulfasalazine, tetracycline Parasites- Löffler's syndrome

5. Symptoms Cough Fever Shortness of breath Night sweats Wheezing Weight loss

6. Diagnosis Typically made 7 mo. after sx begin Bronchoalveolar lavage

11. Treatment Option 1: Steroids

12. Treatment Prednisone 40 – 60 mg/day –C–C–C–Continue until Sx and CXR resolved (4-6 weeks) –C–C–C–Cut dose in half (8 weeks) –R–R–R–Reduce by 5 mg every 4 weeks

13. Treatment Maintain patient on minimum possible dose Switch to alternate-day prednisone Add inhaled corticosteroids

14. Treatment High-dose inhaled corticosteroid –B–B–B–Beclometasone dipropionate 1,600 mcg/day

15. References Chronic eosinophilic pneumonia complicated by bronchial asthma and diabetes mellitus successfully treated with suplatast tosilate and high- dose inhaled corticosteroid therapy. Fujimori K, Shimatsu Y et al. Nihon Kokyuki Gakkai Zasshi. 1999 Nov;37(11):903-8. Chronic eosinophilic pneumonia: treatment with inhaled corticosteroids. Minakuchi M, Niimi A et al. Respiration. 2003 Jul-Aug;70(4):362-6. Eosinophilic lung diseases: a clinical, radiologic, and pathologic overview. Jeong YJ, Kim KI et al. Radiographics. 2007 May-Jun;27(3):617-37; discussion 637-9. Chronic eosinophilic pneumonia. Edwards LT, Fulmer JM et al. BUMC Proceedings. 1999;12:67-74. Chronic eosinophilic pneumonia: a review. Alam M, Burki NK. South Med J. 2007 Jan;100(1):49-53.