1. Chapter 12 Structure of Nucleic Acids

2. 12.1 The Primary Structure of Nucleic Acids

3. The chain termination or dideoxy method of DNA sequencing

4. Automated DNA Sequencing

5. 12.2 Secondary Structure of DNA DNA double helix right-handed 10bp per turn 0.34nm d = 2nm

6. Base stacking force

7. antiparallel

9. 12.3 Denaturation and Renaturation of DNA 12.3.1 DNA Denaturation

10. 12.3.2 DNA Renaturation

12. 12.3.3 Nucleic Acid Hybridization 12.3.4 Buoyant Density of DNA

13. Density gradient centrifugation

14. 12.4 Supercoil and Cruciform : Tertiary structure in DNA

15. Relaxed DNA Unwound DNA Superhelix DNA

16. Palindromic sequence cruciform

17. 12.5 Secondary and Tertiary Structure of RNA Unusual bases of RNA

18. 12.5.1 Messenger RNA ( mRNA ) 5`-cap 3`-poly(A) 7-methyl-G-cap

19. 12.5.2 Transfer RNA ( tRNA ) Cloverleaf secondary structure of tRNA

22. Tertiary interactions in yeast phenylalanine tRNA

23. L-shaped tertiary form

24. 12.5.3 Ribosomal RNA ( rRNA )

25. The proposed secondary structure for E.coli 16S rRNA