1. Topic 7 Nucleic Acids and Proteins

2. DNA Structure

3. DNA Structure cont’d

4. DNA Replication

5. Organization of DNA in Eukaryotes Replication Initiation Sites Where the replication of DNA begins (may also be known as O.O.R.)

6. Nucleosomes Globular structures that contain 8 histone proteins, with DNA wrapped around 2 times Are connected to other nucleosomes by another histone protein (H1), known as a linker Essential for packaging DNA for mitosis/meiosis Involved in gene regulation

7. DNA Folding

9. Repetitive Sequences Repetitive base sequences that are not translated Sometimes called satellite DNA Sequences between 5-300 bp May be repeated as much as 10,000x Constitute 10-40% of euk. genomes Function unknown A vey small portion of euk. DNA is single copy/unique genes

10. Introns and Exons